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2026-04-21
04:35
Apple: John Ternus Appointed as New CEO, Tim Cook to Become Executive Chairman

Apple (AAPL.US) announced on Monday that John Ternus, Senior Vice President of Hardware Engineering, will succeed Tim Cook as Chief Executive Officer (CEO), while Cook will transition to the role of Executive Chairman on September 1.

Cook, who has served as CEO since 2011, will continue in his current capacity until the end of the summer. During this period, he will work closely with Ternus to ensure a smooth leadership transition.
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04:07
Nasdaq Snaps 13-Day Winning Streak as Markets Await US-Iran Ceasefire Deadline; Russell 2000 Hits Record Close Against Trend

The US seized an Iran-flagged cargo vessel over the weekend, heightening geopolitical risks. Meanwhile, the S&P 500 rebounded to a record high last week, and the three major US stock indices edged lower on Monday.

The Nasdaq dipped only 0.3%, or 64 points, to close at 24,404, snapping its 13-day winning streak. The S&P 500 declined 16 points, or 0.2%, to 7,109. The DJIA lost 4 points to 49,442.

However, small-cap stocks outperformed. The Russell 2000 rose 0.6% to 2,792, marking a record closing high, and touched an all-time high intraday.

Software shares advanced, with the iShares Expanded Tech-Software Sector ETF gaining more than 1%. Tesla (TSLA.US) dived nearly 2%, while Intel (INTC.US) dropped 4%.
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2026-04-20
21:30
Hesai Unveils Picasso 6D Full-Color SPAD-SoC, Next-Gen ETX, and Innovations in Spatial Intelligence and Physical AI

Hesai announces a strategic shift to spatial intelligence, introducing Kosmo, a new spatial intelligence AI hardware platform, alongside robotic actuation modules and innovations for the Physical AI era.

PALO ALTO, Calif., April 20, 2026 /PRNewswire/ -- Hesai Technology (Nasdaq: HSAI; HKEX: 2525), a global leader in intelligent technology and 3D perception, hosted its 2026 Technology Open Day on April 17, showcasing its latest generation of lidar technologies spanning full-color perception, ultra-high-resolution imaging, and spatial intelligence applications.

A key highlight was Picasso, the world's first 6D full-color ultra-sensitive lidar SPAD-SoC, enabling native fusion of spatial and color perception at the ASIC level. Built on this platform, Hesai's ETX lidar series has been upgraded to support up to 4320 channels and is expected to enter mass production in the second half of 2026. The company also previewed Kosmo, a new spatial intelligence AI hardware product, and outlined a new direction in robotic actuation modules for physical AI systems.

Picasso - The World's First 6D Full-Color Ultra-Sensitive Lidar ASIC Platform

At the core of today's announcement is Picasso, Hesai's fifth-generation 6D full-color ultra-sensitive lidar ASIC platform, designed to enable vehicles to see both geometry and color natively on a single chip.

Unlike conventional lidar systems that capture only geometric information such as XYZ, Picasso integrates RGB sensing and time-of-flight (ToF) ranging at the chip-level, enabling the direct generation of colorized point clouds without the need for complex sensor fusion. This 6D full-color capability delivers precise spatial and temporal alignment, resulting in richer environmental understanding and significantly enhancing the perception capabilities of next-generation autonomous systems.

Hesai Picasso - The World’s First 6D Full-Color Ultra-Sensitive Lidar ASIC Platform
Hesai Picasso - The World’s First 6D Full-Color Ultra-Sensitive Lidar ASIC Platform

With photon detection efficiency (PDE) exceeding 40%, Picasso delivers industry-leading sensitivity, enabling stronger long-range performance, better detection of small objects, and improved performance in low-light environments within the same power envelope.

Rather than simply combining camera imagery with lidar point clouds, Picasso enables true ASIC-level fusion, with each point inherently carrying color information. This allows autonomous systems to move from spatial perception to real-time understanding of the driving environment, improving performance in different scenarios such as traffic signals, lane markings, and construction zones.

The introduction of Picasso marks a major step in lidar development, moving beyond incremental improvements in resolution toward a new generation of full-color perception. This breakthrough is supported by Hesai's long-term vertical integration strategy and in-house development across core lidar technologies. Following the launch of Fermi C500, a RISC-V-based high-performance lidar controller SoC that integrates MCU, FPGA functions, and ADC into a single chip, the company has established full-stack in-house ASIC development capabilities. This technology foundation has already translated into large-scale commercialization, with Hesai's upgraded ATX lidar achieving full-scale mass production and securing over 6 million units in orders from leading OEMs.

Today, Hesai is the only lidar company in the world to develop all seven core components in-house, including its laser transmitter, receiver, driver, TIA, ADC, digital signal processor, and controller. To date, 21 of its in-house designs have achieved AEC-Q automotive-grade certification, with cumulative shipments exceeding 230 million units and expected to surpass 300 million units by the end of 2026.

According to global IP consultancy KnowMade, Hesai ranks No.1 worldwide in both patent volume and overall patent strength, with leading positions across key device categories including SPAD/SiPM detectors, VCSEL transmitters, and APD detectors. In the SPAD/SiPM segment, Hesai's patent portfolio is approximately twice that of Bosch, the second-ranked company, and up to forty times larger than that of other industry peers.

ETX Platform Upgraded to Full-Color Perception with 1000+ Channels

As the flagship lidar platform built on the Picasso architecture, the next-generation ETX represents a major step forward in high-performance perception. Designed for L3 and above autonomous driving, it combines longer range, higher resolution, and full-color perception in a flexible architecture with 1,080, 2,160, and up to 4,320 channels. With ultra-long-range detection and high-resolution perception, ETX enables vehicles to see farther and capture more detail across complex driving environments.

With a maximum detection range of up to 600 meters and 400 meters at 10% reflectivity, ETX delivers industry-leading performance in both range and small-object detection. It enables high-confidence identification of critical road elements at long distances, including objects as small as a 15 × 25 cm wooden block at 150 meters, significantly improving safety margins.

Built on the Picasso platform, ETX integrates Hesai's latest perception technologies to further enhance performance and reliability. These include upgraded Addressable Photon Isolation technology, advanced signal processing through the Intelligent Point Cloud Engine (IPE), and an enhanced anti-interference design, enabling more accurate signal extraction while suppressing noise and reducing false positives and false negatives compared with conventional SPAD-based approaches, significantly enhancing system safety and reliability.

ETX is expected to enter mass production in the second half of 2026, with planned deployment across multiple flagship vehicle models, supporting the large-scale adoption of L3 autonomous driving systems.

From Automotive to Robotics: Enabling the Physical AI Era

Hesai continues to lead the automotive lidar market in China and globally. According to Gasgoo Research Institute, the company held over 40% market share in 2025, ranking first in the industry, and maintained strong momentum into 2026, reaching a 51% share in February, 2.2 times that of the second-ranked player and more than three times that of the third, and extending its market leadership to 13 consecutive months. To date, Hesai has secured production design wins for more than 160 models across 40 automotive brands.

Hesai is extending its leadership beyond automotive into robotics and embodied AI, with lidar solutions deployed across applications including delivery robots, cleaning robots, automated guided vehicles (AGVs), and robotaxi platforms. The company ranks No. 1 globally across multiple robotics lidar segments and is the only lidar company named to Morgan Stanley's "Humanoid Tech 25" list.

As Physical AI systems scale globally, demand for high-performance perception continues to accelerate. Morgan Stanley estimates that lidar demand could reach 700 million units by 2050, driven by more than 1.4 billion robots, highlighting the growing role of lidar as a core enabling technology for next-generation intelligent systems.

Hesai's global capabilities form the foundation for scaling its lidar and Physical AI strategy. The company has been selected by NVIDIA as a key partner for the NVIDIA DRIVE Hyperion 10 platform. By leveraging the standardized sensor architecture of Hyperion 10, OEMs can accelerate the development and deployment of autonomous driving systems in a safer, faster, and more scalable way. Backed by clear structural advantages in scalability, quality management, and cost, Hesai has established a leading global market position. This is supported by robust product development, manufacturing, and supply chain processes, as reflected in its A-grade result in a VDA 6.3 process audit, with a 90+ audit score. Today, its lidar solutions are enabling Physical AI applications across industries in over 40 countries worldwide.

Kosmo & Robotic Actuation Modules - From Perception to Intelligence

Hesai also previewed Kosmo, a new spatial intelligence AI hardware platform scheduled for release later this year. Designed to capture the 3D world in high fidelity, bringing the physical world into the digital space for immersive and interactive experiences, Kosmo enables scalable spatial data generation and processing. It helps address the shortage of high quality real world data and accelerates the development of world models and embodied AI systems.

Kosmo powers applications across home design, robotics training and many more. In home design, it transforms real spaces into fully interactive digital environments with precise spatial measurements, allowing users to explore from any perspective, rearrange furniture, and adjust lighting in real time. In robotics training, it creates a high-fidelity digital environment where robots can explore, interact, and learn through trial and error, simulating real-world physics to accelerate embodied intelligence.

Hesai also previewed Kosmo, a new spatial intelligence AI hardware platform
Hesai also previewed Kosmo, a new spatial intelligence AI hardware platform

In addition, Hesai unveiled a new strategic direction in robotic actuation modules, core infrastructure for the era of Physical AI. The company has moved into the underlying architecture of robotic actuation modules and independently developed key technologies in this domain. As the Physical AI wave accelerates, robotics is entering a critical stage of real-world understanding and interaction. From the "eyes" of robots to their "muscles," Hesai is expanding its capabilities across intelligent robotics, autonomous driving, smart industrial systems, and broader applications, positioning itself as a key enabler of the Physical AI ecosystem.

Hesai unveiled a new strategic direction in robotic actuation modules, core infrastructure for the era of Physical AI
Hesai unveiled a new strategic direction in robotic actuation modules, core infrastructure for the era of Physical AI

This evolution reflects Hesai's broader strategic expansion from spatial perception to spatial intelligence, moving beyond helping machines sense the world to supporting how they interpret and interact with it, while enabling emerging applications such as world models, embodied intelligence, AI hardware, immersive interaction, AIGC and 4D entertainment.

 

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18:05
Tencent Music Entertainment Group Releases 2025 ESG Report

SHENZHEN, China, April 20, 2026 /PRNewswire/ -- Tencent Music Entertainment Group ("TME", or the "Company") (NYSE: TME and HKEX: 1698), the leading online music and audio entertainment platform in China, today released its 2025 Environmental, Social and Governance ("ESG") Report, detailing the strategic actions taken to drive its sustainability agenda.

Mr. Cussion Pang, Executive Chairman of TME, commented, "The solid execution of our dual content-and-platform strategy has pushed the boundaries of value creation for users, artists, and partners across the music ecosystem, charting new pathways for industry advancement. Looking ahead, we will continue to harness the power of music and technology to create lasting positive impact, fostering a sustainable future for the music industry and society at large."

To access the Company's 2025 ESG Report, please visit: https://ir.tencentmusic.com/ESG-Reports.

About Tencent Music Entertainment

Tencent Music Entertainment Group (NYSE: TME and HKEX: 1698) is the leading online music and audio entertainment platform in China, operating the country's highly popular and innovative music apps: QQ Music, Kugou Music, Kuwo Music and WeSing. TME's mission is to create endless possibilities with music and technology. TME's platform comprises online music, online audio, online karaoke, music-centric live streaming and online concert services, enabling music fans to discover, listen, sing, watch, perform and socialize around music. For more information, please visit ir.tencentmusic.com.

Safe Harbor Statement

This press release contains forward-looking statements. These statements are made under the "safe harbor" provisions of the U.S. Private Securities Litigation Reform Act of 1995. Statements that are not historical facts, including statements about the Company's beliefs and expectations, are forward-looking statements. Forward-looking statements involve inherent risks and uncertainties, and a number of factors could cause actual results to differ materially from those contained in any forward-looking statement. In some cases, forward-looking statements can be identified by words or phrases such as "may," "will," "expect," "anticipate," "target," "aim," "estimate," "intend," "plan," "believe," "potential," "continue," "is/are likely to" or other similar expressions. Further information regarding these and other risks, uncertainties or factors is included in the Company's filings with the SEC and the HKEX. All information provided in this press release is as of the date of this press release, and the Company does not undertake any duty to update such information, except as required under applicable law.

Investor Relations Contact
Tencent Music Entertainment Group
[email protected]
+86 (755) 8601-3388 ext. 885034

 

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17:39
Zoomlion Accelerates Global Deployment of Ultra-Large Hydraulic Excavators and Smart Mining Solutions

CHANGSHA, China, April 20, 2026 /PRNewswire/ -- Zoomlion Heavy Industry Science & Technology Co., Ltd. ("Zoomlion" or the "Company"; 1157.HK) has unveiled the latest advancements in its ultra-large hydraulic excavator portfolio and intelligent mining equipment lineup. This reinforces its commitment to building the next generation of efficient, safe, and sustainable mining operations worldwide.

Zoomlion delivers autonomous mining trucks to a major open-pit mine, supporting smarter mining operations
Zoomlion delivers autonomous mining trucks to a major open-pit mine, supporting smarter mining operations

With global mining projects trending towards larger scale, higher efficiency, and lower emissions, Zoomlion continues to expand its presence in the 100-ton-and-above excavator segment through technological innovation and integrated system solutions. The Company has developed a comprehensive product range spanning 60 to 1,000 tons, including the ZE1050G to ZE2000G series, as well as heavy-duty equipment such as the 400-ton ZE4000G ultra-large excavator, the 35m³ ZRS35G electric shovel, and the hybrid electric-drive ZTE520 mining dump truck.

Together with equipment development, Zoomlion is advancing the green and intelligent transformation across mining operations. The Company is promoting electrification, hybrid power, and hydrogen energy pathways, while introducing megawatt-level ultra-fast charging and mobile energy replenishment systems to improve operational efficiency and reduce carbon intensity. Zoomlion has also established an integrated technology ecosystem spanning "Smart Vehicle, Smart Driving, Smart Mine, and Smart Logistics," enabling remote operation, fault early warning, and predictive maintenance across entire mining fleets.

Among its latest innovations, the ZT115DPEV wide-body battery trolley truck features a dual power system combining overhead line and battery supply, helping reduce charging constraints in mining operations while improving efficiency and route flexibility. The ZT160HEV intelligent mining truck has also demonstrated 24/7 autonomous operation in cold-region mines, with more than 120 units deployed in temperatures as low as minus 30 degrees Celsius, supporting stable performance in harsh, high-dust environments.

Wu Yuanfeng, Deputy General Manager of Zoomlion Earthmoving Machinery Co., shared: "Our strategy goes beyond equipment manufacturing. We are committed to delivering optimal lifecycle value through the integration of intelligent systems, electrification technologies, and full-process service capabilities. By focusing on reliability, energy efficiency, and smart operations management, we are helping customers reduce total operating costs while enhancing safety and productivity."

In 2025, Zoomlion Earthmoving Machinery achieved rapid growth, with domestic sales growing against market trends and international sales tripling. With continued investment in advanced manufacturing, digitalization, and green technologies, Zoomlion is strengthening its role in shaping the future of intelligent and sustainable global mining.

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10:24
Tesla: No Current Plan to Churn out Robots at Shanghai Gigafactory

Regarding hearsay that Tesla (TSLA.US) is set to churn out robots in Shanghai, Securities Times learned from Tesla China that the company currently has no specific plan to mass produce robots at its Shanghai Gigafactory, describing reports claiming that Tesla is about to mass produce robots in Shanghai as incorrect information.
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AASTOCKS Financial News
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09:12
Meta Reportedly Plans to Lay Off 10% of Global Workforce Next Mth, Affecting ~8K Employees w/ Further Job Cuts in 2H26

Meta (META.US) plans to launch its first wave of large-scale layoffs this year on 20 May, with more job cuts later, Reuters quoted sources as saying.

The first round of layoff will reduce about 10% of the Company's global workforce, affecting nearly 8,000 employees, sources noted. The Company also plans further layoffs in 2H26, although specific details such as timing and scale have yet to be finalized. Executives may adjust their plans depending on developments in AI technology.

Earlier reports indicated that Meta was planning to lay off 20% or more of its global workforce.
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2026-04-18
10:38
再鼎醫藥公布最新數據,顯示Zocilurtatug Pelitecan (Zoci) 在小細胞肺癌腦轉移患者中實現快速且顯著的顱內緩解,並在其他神經內分泌癌中展現出良好活性

  • Zoci,一款潛在同類首創的DLL3靶向抗體藥物偶聯物(ADC),在小細胞肺癌(SCLC)腦轉移患者中顯示出53.7%的確認顱內客觀緩解率(iORR);在1.6mg/kg劑量下,確認的iORR62.5%10/16),包括顱內腫瘤完全緩解的病例
  • 在肺外神經內分泌癌(NECs)中觀察到令人鼓舞的活性,經確認的客觀緩解率為38.2%
  • 針對二線及以上小細胞肺癌(SCLC)的全球3期研究正在進行中;一線SCLC和肺外神經內分泌癌項目將於2026年進入注冊性研究階段
  • 投資者電話會議和網絡直播將於420日(星期一)北京時間下午8:30(美國東部時間420日上午8:30/太平洋時間上午5:30)舉行,介紹在2026 AACR年會上公布的數據及後續臨床研究計劃

上海和馬薩諸塞州劍橋2026年4月18日 /美通社/ -- 再鼎醫藥有限公司(納斯達克股票代碼:ZLAB;香港聯交所股份代號:9688)今日宣布的臨床數據表明,靶向DLL3的ADC zocilurtatug pelitecan(zoci,前稱ZL-1310),在既往接受過治療的廣泛期小細胞肺癌(ES-SCLC)腦轉移患者中,經獨立評估采用改良版神經腫瘤腦轉移緩解評估(mRANO-BM)標准衡量,達到快速且顯著的顱內緩解,同時在其他神經內分泌癌(NECs)患者中顯示出有前景的數據。這些研究結果,以及ZL-6201(LRRC15 ADC)和ZL-1222(PD-1/IL-12)的臨床前數據,將在於聖地亞哥舉行的2026美國癌症研究協會(AACR)年會上公布。

一項正在進行的全球1期研究(NCT06179069)的結果表明,接受zoci治療可使腫瘤已轉移至大腦的ES-SCLC患者的顱內病灶顯著消退,該患者群體生存率低且缺乏有效治療選擇。

西班牙馬德裡12 de Octubre大學醫院腫瘤內科主任、西班牙國家癌症研究中心(CNIO)肺癌單元負責人Luis Paz-Ares博士表示:「對於發生腦轉移的廣泛期小細胞肺癌患者來說,腦轉移是導致疾病進展常見且具有重要臨床意義的驅動因素,其預後不佳,現有的治療方案不僅會延遲全身治療,且療效有限。正在進行的zoci的臨床數據令人鼓舞,不僅在多個劑量組中顯示出快速且顯著的緩解,而且無論患者既往是否接受過顱內放療,都顯示出顯著的活性。這些結果表明,zoci有望為治療選擇有限、難以治療的癌症提供一種新的治療選擇,滿足該患者群體未被滿足的巨大醫療需求。」

此外,研究人員還將分享一項zoci在肺外神經內分泌癌(epNEC)和其他選定實體瘤患者中的1b/2期臨床研究(NCT06885281)的初步數據。這些數據表明,zoci在這一類侵襲性強、預後差且治療選擇有限的惡性腫瘤患者群體中具有抗腫瘤活性,客觀緩解率(ORR)為38.2%。值得注意的是,目前經治的epNEC尚無獲批的標准治療方案。在這種癌症中也無靶向療法。

摘要標題:靶向DLL3ADC ZL-1310在經治的廣泛期小細胞肺癌伴基線腦轉移患者中的顱內活性:一項1期研究分析

該研究入組了伴有基線腦轉移的ES-SCLC患者,接受不同劑量(0.8、1.2、1.6、2、2.4或2.8 mg/kg)的zoci單藥治療,每三周靜脈給藥一次。數據的中位隨訪時間為7.9個月。全身性有效性采用研究者評估的RECIST v1.1標准,顱內有效性則由盲態獨立影像學委員會依據mRANO-BM來進行評估。

  • 在136名接受治療的患者中,36%在進入研究前的基線已存在腦轉移。
  • 在所有存在腦轉移且有機會完成至少兩次基線後掃描的患者中,接受zoci治療的患者顱內客觀緩解率(iORR)為53.7%(22/41),其中包括7例完全緩解。在1.6mg/kg劑量下,經確認的iORR為62.5%(10/16),包括4例完全緩解。14例患者在中位隨訪9.2個月時尚未出現進展或死亡事件(刪失)。
  • 多個劑量水平組均出現顱內腫瘤縮小,並且在既往接受過放療(50%,13/26)和未接受過放療(60%,9/15)的患者中均觀察到了緩解。
  • Zoci表現出可控的安全性特征,報告的大多數治療期出現的不良事件(TEAEs)為低級別,停藥極少。在總人群≥3級治療相關不良事件(TRAEs)發生率為19.9%(27/136),而接受1.6mg/kg劑量患者為16.4%(9/55)。最常見的≥3級TRAEs包括:中性粒細胞減少症(9.6%,13/136)、貧血(8.8%,12/136)、血小板減少症(3.7%,5/136)、淋巴細胞減少症(2.9%,4/136)、白細胞減少症(2.9%,4/136)。未報告顱內轉移並發症或治療相關的神經系統嚴重不良事件。

摘要標題:靶向DLL3ADC ZL-1310在神經內分泌癌和其他特定實體瘤患者中的1b/2期、開放標簽、多中心研究的初步結果

在另一項針對因侵襲性惡性腫瘤且治療選擇有限而存在高度未滿足需求的患者的重要分析中,zoci用於NECs患者的多中心1b/2期研究的初步結果顯示出具有臨床意義的緩解。研究人員以1.6mg/kg的劑量每三周靜脈注射一次zoci,直至疾病進展或出現不可接受的毒性,數據截止日期為2026年2月18日,研究1b期部分的中位隨訪時間為3.7個月。腫瘤反應由研究者根據RECIST v1.1標准評估,並對部分NECs進行了額外評估。

  • 在46名既往接受過鉑類化療和其他全身治療的患者中,zoci治療使多個肺外神經內分泌癌(epNEC)亞型的腫瘤體積縮小,且在經治患者中觀察到確認的緩解。
  • 在可評估緩解的患者中,所有研究隊列的總客觀緩解率為38.2%(13/34),總疾病控制率為55.9%(19/34)。
  • Zoci表現出可控的安全性特征;中性粒細胞計數下降(5.2%,3/58)是目前唯一在超過一名患者中發生的≥3級TRAE。

這些研究結果凸顯了zoci在多種表達DLL3的神經內分泌癌中的廣泛潛力。

再鼎醫藥總裁,全球研發負責人Rafael G. Amado博士表示:「我們將在AACR上公布的zoci數據,連同我們的ZL-6201和ZL-1222臨床前數據,共同凸顯了再鼎醫藥全球腫瘤研發管線的廣度、多樣性和潛力。Zoci快速進入關鍵性開發階段,計劃在今年年底前啟動三項注冊性研究,這是我們努力實現首個腫瘤產品全球上市戰略的印證。這一加速進展得益於我們獨特的中美一體化架構,使我們能夠聚焦速度和質量,將藥物發現轉化為改變生命的藥物。」

再鼎醫藥內部開發的另外兩款在研腫瘤療法的數據也將在AACR上公布。研究人員將分享ZL-6201(一款靶向富含亮氨酸重復序列蛋白15(LRRC15)的ADC,用於治療表達LRRC15的癌症相關成纖維細胞的肉瘤和上皮瘤)和ZL-1222(一種潛在的下一代抗PD-1/白細胞介素-12(IL-12)信號減弱突變體激動劑免疫細胞因子,用於癌症免疫治療)臨床前研究中令人鼓舞的發現。

網絡直播和電話會議的詳細信息如下: 
日期/時間:2026年4月20日,星期一,太平洋時間上午5:30 / 美國東部時間上午8:30 / 北京時間晚上8:30

注冊鏈接:
網絡直播(推薦)https://edge.media-server.com/mmc/p/8v9n78fj/
電話撥入: https://register-conf.media-server.com/register/BId10f18579c7947b29fda2857a99f26b9
演講人再鼎醫藥總裁,全球研發負責人Rafael G. Amado博士;西班牙馬德裡12 de Octubre大學醫院腫瘤內科主任、西班牙國家癌症研究中心(CNIO)肺癌單元負責人Luis Paz-Ares博士;紀念斯隆-凱特琳癌症中心胃腸腫瘤內科醫生Rohit Thummalapalli博士

關於Zocilurtatug Pelitecan (zoci, 前稱ZL-1310)

Zoci是一款靶向DLL3的新型ADC。DLL3是一種經過驗證的小細胞肺癌(SCLC)治療靶點,也在多種神經內分泌腫瘤中過度表達,通常與不良臨床預後相關。Zoci有望成為再鼎醫藥首個全球上市的抗腫瘤產品,計劃到2026年底開展三項注冊性研究,涉及二線及以上SCLC、一線SCLC以及肺外神經內分泌癌。Zoci具有潛在的同類最佳安全性特征,以及明確的全身性和顱內療效,支持其有望成為既往接受過治療的廣泛期小細胞肺癌(ES-SCLC)的新標准治療,並作為靶向DLL3的抗體偶聯藥物(ADC)基石,用於一線聯合治療方案,包括用以降低化療毒性負擔的治療方案,如聯合免疫檢查點抑制劑和T細胞銜接器。

關於ZL-6201

再鼎醫藥正在評估ZL-6201作為一款有望成為同類首創的靶向LRRC15抗體藥物偶聯物,用於治療多種實體瘤。LRRC15是一種I型跨膜蛋白,在多種間充質腫瘤(如肉瘤、膠質母細胞瘤和黑色素瘤)以及許多其他腫瘤類型的癌相關成纖維細胞中過度表達,是一個具有吸引力的癌症治療靶點。

關於ZL-1222

ZL-1222是一款潛在的新一代雙特異性免疫細胞因子,由抗PD-1抗體和抗體融合活性降低的IL-12組成,再鼎醫藥正在評估其用於多種適應證的癌症免疫治療,其有望在發揮強效抗腫瘤活性的同時改善全身安全性。此前,白介素-12療法已在多種癌症類型中顯示出潛在獲益,但狹窄的治療窗口和毒性問題限制了這類治療藥物的應用。

關於再鼎醫藥

再鼎醫藥(納斯達克股票代碼:ZLAB; 香港聯交所股份代號:9688)是一家以研發為基礎、處於商業化階段的創新型生物制藥公司,總部位於中國和美國。我們致力於通過創新產品的發現、開發和商業化解決腫瘤、免疫、神經科學和感染性疾病領域未被滿足的巨大醫療需求。我們的目標是利用我們的能力和資源為人類健康帶來積極影響。

有關再鼎醫藥的更多信息,請訪問www.zailaboratory.com或關注https://x.com/ZaiLab_Global

再鼎醫藥前瞻性聲明

本新聞稿包含關於再鼎醫藥未來預期、計劃和展望的前瞻性陳述,包括但不限於與我們開發和商業化zocilurtatug pelitecan (zoci)、ZL-6201和ZL-1222的前景和計劃、zoci、ZL-6201和ZL-1222的潛在獲益,以及小細胞肺癌、神經內分泌癌和實體瘤的潛在療法有關的陳述。本新聞稿中包含的所有陳述(對過往事實的陳述除外)均為前瞻性陳述,可以通過諸如「旨在」、「預計」、「認為」、「有可能」、「估計」、「預期」、「預測」、「目標」、「打算」、「可能」、「計劃」、「可能的」、「潛在」、「將會」、「將要」等詞匯和其他類似表述加以識別。該等陳述構成《1995年美國私人證券訴訟改革法案》中定義的「前瞻性陳述」。前瞻性陳述並非對未來表現的擔保或保證。前瞻性陳述基於我們截至本新聞稿發布之日的預期和假設,並且受到固有不確定性、風險以及可能與前瞻性陳述所預期的情況存在重大差異的情勢變更的影響。我們可能無法如我們在前瞻性陳述中所做出的披露實際實現計劃、執行意圖,或滿足期望或預測,您不應過分依賴該等前瞻性陳述。實際結果可能受各種重要因素的影響而與前瞻性陳述所示存在重大差異,該等因素包括但不限於:(1)我們成功商業化自身已獲批上市產品並從中產生收入的能力;(2)我們為自身的運營和業務活動獲取資金的能力;(3)我們候選產品的臨床開發和臨床前開發的結果;(4)相關監管機構對我們的候選產品作出審批決定的內容和時間;(5)與在中國營商有關的風險;和(6)我們向美國證券交易委員會(SEC)提交的最新年報和季報以及其他報告中指出的其他因素。我們預計後續事件和發展將導致我們的預期和假設改變,但除法律要求之外,不論是出於新信息、未來事件或其他原因,我們均無義務更新或修訂任何前瞻性陳述。該等前瞻性陳述不應被視為我們在本新聞稿發布之日後任何日期的意見而加以信賴。

如需查閱公司向SEC提交的文件,請訪問公司網站www.zailaboratory.com和SEC網站www.SEC.gov

Information Provided by PR Newswire [Disclaimer]
2026-04-17
22:13
Shanghai Electric Reports Strong 2025 Performance, New Orders Hit Record High

SHANGHAI, April 17, 2026 /PRNewswire/ -- Shanghai Electric (SEHK: 02727, SSE: 601727) announced its 2025 performance results, reporting revenue of RMB 126.68 billion (USD 18.58 billion), marking a 9.03% year-on-year increase. The net profit attributable to shareholders of the listed company reached RMB 1.206 billion (USD 176.92 million), a surge of 60.37% year-on-year. The total value of new orders received throughout the year amounted to RMB 172.81 billion (USD 25.35 billion), up 12.50% year-on-year, hitting a record high.

 

At the annual results briefing held on April 2 in Hong Kong, Shanghai Electric presented the company's 2025 performance and key financial data, while engaging with a wide range of institutional investors and analysts on business developments and future plans. The company delivered solid performance across core operating metrics in 2025, with notable improvements in overall business quality, driven by breakthroughs in new orders, technological innovation, and segment synergy.

Strong growth in profitability, new orders, and segment revenue

In 2025, Shanghai Electric achieved critical breakthroughs in emerging sectors, accelerated the execution and deployment of independent innovations in high-end manufacturing, and continued to deepen its global market presence.

The group's total operating profit reached RMB 5.02 billion (USD 736.73 million), up 34.28% year-on-year. Basic earnings per share stood at RMB 0.078, a significant increase of 62.50%.

The energy equipment segment generated revenue of RMB 75.02 billion (USD 11.01 billion), up 21.48% year-on-year, continuing to consolidate its industry leadership position.

Significant growth was achieved in the high-growth business sectors:

  • Wind power equipment orders reached RMB 22.966 billion (+32.18%, USD 3.37 billion);
  • Nuclear power equipment orders hit RMB 9.888 billion (+25.37%, USD 1.45 billion);
  • Gas power generation equipment orders amounted to RMB 3.095 billion (+33.35%, USD 454.04 million);
  • Power station service orders came in at RMB 7.312 billion (+45.28%, USD 1.07 billion).

Strengthened innovation capabilities and emerging sector breakthroughs

Shanghai Electric has achieved significant technological breakthroughs in new areas, including green methanol, green hydrogen, energy storage, and superconducting power, steadily improving its level of technological independence.

In high-end manufacturing, self-developed innovative products such as humanoid robots, industrial machine tools, and precision bearings are accelerating market application, further strengthening the company's core capabilities in this sector.

With research and development expenses reaching RMB 6.164 billion (USD 904.26 million) in 2025, Shanghai Electric's sustained high investment in R&D continues to underpin technological innovation and product upgrades.

Advancing industrial optimization and global market presence

In response to investor inquiries regarding its robotics deployment, aviation equipment business development, nuclear power equipment exports, coal-fired power tender outlook, and gas turbine exports, Shanghai Electric reaffirmed its commitment to further strengthening its position in energy equipment, enhancing the operational efficiency of industrial equipment, and expanding its global integrated service capabilities.

  • Traditional energy: to strengthen grid regulation capabilities and advance low-carbon upgrades, while accelerating the engineering deployment of nuclear power and nuclear fusion technologies.
  • High-end manufacturing: to scale up the development of robotics, aerospace equipment, and advanced machine tools, with a focus on achieving breakthroughs in key core technologies.
  • Overseas growth: to deepen its presence in overseas markets while enhancing its capabilities across desalination, power transmission and distribution, and energy equipment.

Executing 2026 priorities through innovation and digital transformation

In 2026, Shanghai Electric will continue to enhance core competitiveness with technological innovation as the primary engine, digital transformation as the main strategic direction, and green development as the foundation, to pursue high-end upgrades in traditional industries, scale up strategic emerging sectors, and make forward-looking moves in future industries.

Information Provided by PR Newswire [Disclaimer]
21:16
MGM Returns to Art Basel Hong Kong with an Immersive Showcase of Macau's Cultural-Tourism Landscape

Nurturing Arts Talent
Hong Kong–Macau Synergy Expands International Exchange Networks

HONG KONG, April 17, 2026 /PRNewswire/ -- MGM reaffirmed its long‑standing partnership with Art Basel Hong Kong this week, leading delegations of Macau cultural leaders, arts professionals, and university faculty and students to the fair for exclusive guided tours and dialogue sessions. The initiative aligns with the direction of China's "15th Five‑Year Plan", which calls for high‑quality cultural‑tourism development and advances the goal of helping Chinese culture go global. It also underscores the role of Hong Kong and Macau as key platforms for international cultural exchange.

The winner of the 2026 MGM Discoveries Art Prize is revealed with the award presented to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.
The winner of the 2026 MGM Discoveries Art Prize is revealed with the award presented to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.

As a pioneer in cultural‑tourism innovation, MGM has championed local arts development and talent cultivation for many years. Since forming a long‑term partnership with Art Basel Hong Kong in 2017, the Company has continued to build a bridge between Macau's arts community and the global stage, strengthening regional collaboration. This year, MGM once again served as a "super‑connector", drawing together artistic voices and cultural resources from Hong Kong and around the world. Encountering world‑class artworks at close range allowed participants to widen their global horizons, spark fresh ideas for Macau's arts development, and deepen the city's connection to international cultural networks.

This year, MGM also partnered with BOE, a global leader in display technology, to present an immersive showcase at its dedicated booth. The installation uses an "M‑shaped" four‑fold high‑definition, small‑pixel‑pitch LED display that combines intelligent energy efficiency with exceptional image clarity. Together with cutting‑edge naked‑eye 3D technology, it vividly brings to life a range of Macau's cultural‑tourism projects and highlights the diverse appeal of the city's integrated "culture + tourism + technology" development for the international arts community.

Cultivating a Fertile Environment for Macau's Arts Talent

Yesterday (March 26), MGM led a delegation of over 20 Macau cultural leaders, artists, and industry representatives to the VIP preview, where they engaged in in-depth exchanges with representatives from participating galleries. Today (March 27), MGM further welcomed 30 young local artists, arts students and faculty members to visit the fair and join the "Conversations" talks program, a signature highlight of Art Basel. They heard insights from renowned collectors and cultural leaders such as Saeb Eigner and Uli Sigg, exploring themes ranging from art collecting and cultural diplomacy to cross-regional exchange. The sessions deepened participants' understanding of Asian art development and the global arts ecosystem, while offering a close-up sense of the international art market's pulse.

MGM China Holdings Limited Chief Executive Officer and Executive Director Kenneth Xiaofeng Feng said: "MGM remains committed to leveraging Macau's unique role as a vital gateway for cultural exchange between East and West. Through our global network, we continue to create platforms that connect Macau's arts community with the world, helping industry professionals gain deeper insights into global art market trends and the practical dynamics of the art economy. We will continue strengthening our collaborations with the international cultural and arts sector, supporting Macau's moderate diversified economic development, and showcasing the city's immense potential in cultural‑tourism integration."

Zhu Jiao, who is currently pursuing a Doctor of Fine Arts at the University of Macau and participated in the exchange, said: "Having transitioned from MGM's National Arts Fund training program to attending Art Basel today, I can truly see how MGM continuously empowers young art professionals and students in Macau by building bridges to the global stage. These platforms allow us to immerse ourselves in the global art ecosystem and understand market dynamics firsthand. Such rare opportunities and valuable experiences are of great significance in broadening our creative horizons and helping us reflect on our future career development."

Cutting Edge Technology Animates Macau's Diverse Cultural Tourism Projects

MGM unveiled an innovative "M-shaped" four-fold high-definition, small-pixel-pitch LED display at the fair, using cutting-edge technology to break away from the limitations of traditional flat screens. The installation creates a sense of visual extension and a hyper-real, immersive virtual space, vividly re-creating precious artefacts from the "Silk Roads Beyond Borders" exhibition at the POLY MGM MUSEUM—including emblematic works such as the Blue-and-White Moon Flask with Strap Handles and the Dragon-Patterned Throne Carpet—alongside leading modern and contemporary artworks.

Highlights from MGM's resident production Macau 2049, which blends intangible cultural heritage with modern technology—including scenes such as "Khoomei: Ethereal"—are also brought to life on the screen. The booth further features looping promotional videos from the Macao SAR Government offering visitors an immersive glimpse into Macau's vibrant, innovative, and increasingly diversified cultural-tourism landscape.

2026 MGM Discoveries Art Prize Winner Announced

The winner of the 2026 MGM Discoveries Art Prize was also revealed today (March 27). After a rigorous selection process, the international jury awarded the prize to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.

Angelle Siyang-Le, Director of Art Basel Hong Kong, commented: "At Art Basel Hong Kong, we are committed to connecting artistic voices from Asia with the world and opening up meaningful exchanges across cultures. The MGM Discoveries Art Prize reflects a shared belief between Art Basel and MGM in supporting the next generation of artists and the galleries that stand behind them, while recognizing the originality and energy of emerging practices. We are especially pleased that the prize creates a meaningful opportunity for the winning artist and their gallery to engage with Macau through this rich cultural exchange."

Established jointly by MGM and Art Basel Hong Kong in 2025, the prize aims to identify and support promising emerging artists. The jury comprises five distinguished international arts and culture experts. The winning artist and their representing gallery receive a cash award and an invitation to visit Macau, where the artist will explore the city's unique East meets West cultural landscape, engage in creative exchange with local young artists, and potentially present their work in Macau.

About MGM

MGM is an abbreviation for MGM China Holdings Limited (HKEx: 2282) and is a leading developer, owner and operator of gaming and lodging resorts in Greater China. We are the holding company of MGM Grand Paradise, SA which holds one of the six gaming concessions to run casino games in Macau. MGM Grand Paradise, SA owns and operates MGM MACAU, the award-winning premium integrated resort located on the Macau Peninsula and MGM COTAI, a contemporary luxury integrated resort in Cotai. 

MGM MACAU is a Forbes Five-Star luxury integrated resort inspired by the arts with every element of the resort infused with creativity and style. MGM MACAU has approximately 600 guest rooms and suites and boasts a number of distinguishing features, including the architecturally stunning European-inspired Grande Praça, housed under a soaring glass ceiling. The POLY MGM MUSEUM spanning almost 2,000 square meters, is constructed in accordance with Chinese national standards for the exhibition of Grade-One cultural relics. MGM MACAU's world class facilities also include conference and event facilities, spa, and seven signature restaurants and bars to fulfill any gastronomic craving. Our property is conveniently located on the Macau Peninsula and is directly connected to the luxury retail shopping complex, One Central.

Designed as the "jewelry box" of Cotai, MGM COTAI offers approximately 1,400 hotel rooms and suites, meeting space, high end spa, retail offerings, food and beverage outlets as well as the first international Mansion at MGM for the ultimate luxury experience.  MGM has joined hands with renowned Chinese filmmaker Zhang Yimou to set up the "Macau 2049" residency in MGM Theater. The Spectacle at MGM COTAI becomes the record holder of the largest free-span gridshell glazed roof (self-supporting) on January 19, 2019, making it the first architectural and structural GUINNESS WORLD RECORDS™ title for Macau, China. MGM COTAI is being developed to drive greater product diversification and bring more advanced and innovative forms of entertainment to Macau as it grows as a global tourist destination. MGM COTAI is the only mega complex and hotel in Macau to gain three-star certification in both Green Building Design and Operation Label, as well as the first hotel in the Greater Bay Area and second in Greater China to receive the certifications.

MGM China is majority owned by MGM Resorts International (NYSE: MGM) one of the world's leading global hospitality companies, operating a portfolio of destination resort brands including Bellagio, ARIA, MGM Grand, Mandalay Bay and Park MGM. For more information about MGM Resorts International, visit the Company's website at www.mgmresorts.com.

About Art Basel

Founded in 1970 by gallerists from Basel, Art Basel today stages the world's premier art shows for Modern and contemporary art, sited in Basel, Miami Beach, Hong Kong, Paris, and Qatar. Defined by its host city and region, each show is unique, which is reflected in its participating galleries, artworks presented, and the content of parallel programming produced in collaboration with local institutions for each edition. Art Basel's engagement has expanded through new digital platforms including Zero 10 and the Art Basel App, and initiatives such as the Art Basel and UBS Global Art Market Report and Survey of Global Collecting, Art Basel Awards, and Art Basel Shop. For further information, please visit artbasel.com.

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