The temporary ceasefire between the US and Iran appeared to hold on Monday (27th), although Tehran negated reports that it had agreed to a 10-day ceasefire.

US President Donald Trump has temporarily shelved plans to escalate military operations against Iran owing to concerns over declining inventories of Patriot interceptor missiles and other air defense munitions in the Middle East, the New York Times reported.

NBC News separately reported that the US military has intentionally allowed some Iranian projectiles to pass through defenses in order to preserve missile supplies.

The news dragged oil prices sharply lower. Brent crude futures plunged 8.7% to settle at USD88.36 per barrel. After tumbling 7.5% on Monday, US West Texas Intermediate crude fell another 0.62% early Tuesday, with losses nearing 1% during Asian trading hours.

In addition, NVIDIA Corporation (NVDA.US) and multiple technology companies on Monday launched a new AI security initiative focused on open models, in response to the continuing impact from cyberattacks involving OpenAI models.

Besides NVIDIA, alliance members include Microsoft Corporation (MSFT.US), Space Exploration Technologies Corp. (SPCX.US), Palantir Technologies Inc. (PLTR.US), as well as dozens of technology firms from the US and Europe.
~

AASTOCKS Financial News
Website: www.aastocks.com

OpenAI is discussing a guarantee arrangement of up to USD250 billion with NVIDIA Corporation (NVDA.US) to support its plan to lease large artificial intelligence data centers (AIDCs). CNBC confirmed the report.

The guarantee will allow OpenAI to leverage NVIDIA's credit strength to raise debt financing for a 10-gigawatt data center campus in Pike County, Ohio, according to sources familiar with the matter.

The guarantee will cover leasing and construction debt, but will not include NVIDIA chips used at the campus, with related chip arrangements still under separate discussions between the two parties.

NVIDIA declined to comment. The Wall Street Journal first reported the USD250 billion guarantee negotiations.
~

AASTOCKS Financial News
Website: www.aastocks.com

Investors looking to bet on stocks such as Space Exploration Technologies Corp. (SPCX.US) and Micron Technology, Inc. (MU.US) now have a new tool available - nearly 24-hour trading in single-stock futures.

CME Group on Monday launched cash-settled single-stock futures on 55 US stocks, along with micro contracts on 22 stocks, marking the exchange's entry into a market that allows investors to establish leveraged long or short positions around the clock.

The contracts trade on the CME Globex platform from Sunday evening through Friday afternoon, with a one-hour daily maintenance break, enabling investors to react to earnings results and other market-moving events outside regular US stock market trading hours.

The products include futures linked to SpaceX, which is regarded as one of Wall Street's most closely watched IPO candidates in recent years. Other underlying stocks include Micron, NVIDIA Corporation (NVDA.US), Tesla, Inc. (TSLA.US) and Apple Inc. (AAPL.US).
~

AASTOCKS Financial News
Website: www.aastocks.com

BEIJING, July 28, 2026 /PRNewswire/ -- Baidu, Inc. ("Baidu" or the "Company") (Nasdaq: BIDU; HKEX: 9888 (HKD Counter) and 89888 (RMB Counter)), a leading AI company with strong Internet foundation, today announced that it will hold an extraordinary general meeting of shareholders (the "EGM") at Baidu Campus, No. 10, Shangdi 10th Street, Haidian District, Beijing 100085, People's Republic of China on August 26, 2026 at 9:00 a.m. (Beijing/Hong Kong time), for the purposes of considering and, if thought fit, passing each of the resolutions to be submitted to shareholder approval at the EGM as set forth in the notice of the EGM (the "EGM Notice"). The EGM Notice and the form of proxy for the EGM are available on the Company's website at https://ir.baidu.com.

As previously announced, the board of directors of the Company has fixed the close of business on July 17, 2026, Hong Kong time, as the record date (the "Shares Record Date") of Class A ordinary shares with a par value of US$0.000000625 each (the "Class A Ordinary Shares") and Class B ordinary shares with a par value of US$0.000000625 each (together with the Class A Ordinary Shares, the "Shares"). Holders of record of the Company's Shares as of the Shares Record Date are entitled to attend and vote at the EGM and any adjourned meeting thereof.

Holders of record of American depositary shares (the "ADSs") as of the close of business on July 17, 2026, New York time, who wish to exercise their voting rights for the underlying Class A Ordinary Shares must give voting instructions to The Bank of New York Mellon, the depositary of the ADSs.

The Company has filed its annual report on Form 20-F, including its audited financial statements, for the year ended December 31, 2025 (the "Form 20-F"), with the U.S. Securities and Exchange Commission. The Form 20-F can be accessed on the Company's website at https://ir.baidu.com, as well as on the SEC's website at http://www.sec.gov.

The Company has also published an annual report (the "Hong Kong Annual Report") pursuant to the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited ("HKEx"). The Hong Kong Annual Report contains substantially the same information as set forth in the Form 20-F and can be accessed on the Company's investor relations website at https://ir.baidu.com as well as the HKEx's website at http://www.hkexnews.hk.

About Baidu

Founded in 2000, Baidu's mission is to make the complicated world simpler through technology. Baidu is a leading AI company with strong Internet foundation, trading on Nasdaq under "BIDU" and HKEX under "9888". One Baidu ADS represents eight Class A ordinary shares.

Setting highest annual visitation to date
Offering Macao's largest free sales platform to empower local SMEs
 Drawing 800,000 visits across seven editions

MACAO, July 28, 2026 /PRNewswire/ -- The "2026 Sands Shopping Carnival," an annual signature shopping event in Macao, was held successfully from July 23 to 26 at The Venetian^® Macao's Cotai Expo, drawing large crowds over four consecutive days, attracting nearly 160,000 visits and setting a record-high annual visitation in the event's history. In its seventh edition this year, the carnival has grown to feature over 580 booths across eight themed exhibition zones, the largest-ever food court, and new additions including a "Sports Experience Zone" and a range of cultural and creative brands from the Greater Bay Area – all aimed at offering an enhanced one-stop summer carnival experience for Macao residents and visitors alike. The event once again played a key role in driving footfall and boosting spending across the city, fully supporting the Macao SAR government's "Tourism+" policy, and facilitating the city's economic diversification.

As the largest sales event in Macao, the Sands Shopping Carnival has served as a large business platform for local SMEs, community partners and Sands retailers for seven consecutive years since its launch during the pandemic in 2020. It is dedicated to helping local SMEs expand business opportunities, broaden customer base, and enhance brand visibility. To date, the carnival has provided 4,000 complimentary booths for local businesses and has been highly received among both Macao residents and the Greater Bay Area visitors. Over the past seven years, the event has attracted a cumulative total of 800,000 visits.

This year, the scale of the event has expanded even further, featuring over 580 booths that brought together an array of international and local Macao brands across eight themed exhibition zones: Household Products, Gourmet and Wine, Food Court, Cultural and Creative, Sands Retailers, Macao Specialties and Souvenirs, Play and Fun, and Sports Experience. 

Dr. Wilfred Wong, executive vice chairman of Sands China Ltd., said: "We are delighted to celebrate the successful conclusion of the seventh edition of the Sands Shopping Carnival. Over the past seven years, the carnival has evolved from an innovative SME initiative into Macao's largest consumption event. It stands as a testament to the perseverance and growth of the city's SMEs, while embodying the spirit of solidarity that brings the Macao community together. Over the years, the event has helped local SMEs expand their business opportunities while providing trainees from social service organisations with a valuable platform to apply their skills, showcase their talents and unleash their potential. By uniting the strength of the business, commercial and social service sectors, the event fully demonstrates Macao's vibrancy and diversity. We are especially encouraged that the carnival is drawing an increasing number of visitors from across the Greater Bay Area to Macao, further cementing its position as one of the region's most influential consumer events, attracting 800,000 visits over the past seven years.

"We would like to extend our heartfelt gratitude to the Macao SAR government and all sectors of society for their longstanding support and trust. Looking ahead, Sands China will continue to leverage this platform to create opportunities and strengthen connections among local SMEs and community partners, while remaining committed to supporting Macao's economic diversification and contributing to its development as a World Centre of Tourism and Leisure."

A number of new elements were introduced to this year's carnival, including the largest-ever food court, which brought together 58 popular local eateries and gave visitors an experience of Macao's diverse culinary offerings. A Sports Experience Zone was also set up, allowing the public to enjoy the fun of pickleball. The zone also featured a basketball shooting challenge as a warm-up for the NBA China Games, which is set to take place in October at The Venetian Arena. In addition, the Cultural and Creative Zone welcomed a multitude of cultural and creative brands from the Greater Bay Area for the first time. These themed exhibition zones attracted a steady stream of visitors, creating a lively atmosphere and fully demonstrating the carnival's appeal.

As one of the highlights of the carnival, the ICBC ePay Presents: Greater Bay Area Karaoke King Singing Competition received an overwhelming response once again. The event attracted close to 150 talented singers from the Greater Bay Area. Notably, over half of the applicants were from Hong Kong, reflecting the competition's growing appeal across the Greater Bay Area. Throughout the competition, contestants delivered powerful performances, showcasing impressive vocal talent and captivating stage presence, filling the venue with excitement and enthusiasm. In addition, the Busking Corner, which was open for public participation, attracted many singing enthusiasts to take the stage. Professional singers were also invited to give warm-up performances, further enriching the carnival experience.

This year, Sands China once again invited local social service organisations to participate in the carnival, providing a platform for local disadvantaged groups to showcase their talents and integrate into society. A record high of 20 social service organisations joined this year, covering social rehabilitation, youth development, animal welfare, and support for vulnerable groups. The event provided an opportunity for people with special educational needs and other trainees to gain practical experience by promoting and selling their handmade products, thereby enhancing their skills and confidence. In addition, the company organised a range of community activities to further promote inclusivity in Macao.

Over 5,000 selected items priced at MOP1 and products with 90% discount were available for purchase every day during the event. In addition, a series of family activities were arranged during the carnival. The well-received cooking activity "BOC Smart Kids Presents: Little Master Chef Workshop" returned this year, attracting nearly 3,000 participants over the past seven years. Led by Sands China's food and beverage team, participating families made different cuisines and enjoyed the fun of cooking together. The carnival also featured the Bank of Communications Presents: "Play and Fun" Kids Area, which offered inflatable attractions, game booths, and other exciting activities for children to play freely and for families to strengthen their bonds.

The 2026 Sands Shopping Carnival was organised by Sands China and co-organised by the Macao Chamber of Commerce, with full support from the Economic and Technological Development Bureau (DSEDT), the Macao Government Tourism Office (MGTO), and the Commerce and Investment Promotion Institute (IPIM). The event was sponsored by BOC Macau, ICBC (Macau), Bank of Communications Co., Ltd. Macau Branch, and Banco Nacional Ultramarino (BNU).

About Sands China Ltd.

Sands China Ltd. (Sands China or the Company) is incorporated in the Cayman Islands with limited liability and is listed on The Stock Exchange of Hong Kong Limited (HKEx: 1928). Sands China is the largest operator of integrated resorts in Macao. The Company's integrated resorts on the Cotai Strip comprise The Venetian^® Macao, The Plaza^® Macao, The Parisian^® Macao and The Londoner^® Macao. The Company also owns and operates Sands^® Macao on the Macao peninsula. The Company's portfolio features a diversified mix of leisure and business attractions and transportation operations, including large meeting and convention facilities; a wide range of restaurants; shopping malls; world-class entertainment at The Venetian Arena, The Londoner Arena, The Venetian Theatre, The Parisian Theatre, The Londoner Theatre and Sands Theatre; and a high-speed Cotai Water Jet ferry service between Hong Kong and Macao. The Company's Cotai Strip portfolio has the goal of contributing to Macao's transformation into a world centre of tourism and leisure. Sands China is a subsidiary of global resort developer Las Vegas Sands Corp. (NYSE: LVS).

For more information, please visit www.sandschina.com.

Media contacts:

Corporate Communications, Sands China Ltd.
Mabel Wu
Tel: +853 8118 2268
Email: [email protected]

Jesse Chiang
Tel: +853 8118 2054
Email: [email protected]

創下歷屆入場人數新高

打造全澳最大規模免費展銷平台  助本澳中小微企拓展商機

舉辦七屆至今累計80萬人次入場

澳門2026年7月28日 /美通社/ -- 澳門年度購物品牌盛事 --「2026金沙物美嘉年華」已於7月23日至26日在澳門威尼斯人®金光會展圓滿舉行，一連四天人潮熙攘，共吸引近160,000人次入場參與，創下歷屆入場人數新高。今年邁入第七屆的嘉年華規模持續升級，共設逾580個特色展位及八大主題展區、歷來最大規模的美食廣場，更首度增設「運動體驗」區，亦首次雲集大灣區文創品牌參與，為澳門市民及旅客提供更豐富的一站式盛夏嘉年華體驗。活動持續發揮引流及帶動消費的盛事平台作用，全力配合澳門特區政府「旅遊+」施政方針，助力澳門經濟適度多元發展。

「金沙物美嘉年華」作為全澳最大規模消費折扣展，自2020年疫情期間舉辦以來，連續七年為本澳中小微企、社區合作伙伴及金沙零售商戶搭建大型展銷平台，致力協助本澳中小企開拓商機、拓展客源及提升品牌知名度。活動至今累計為本澳商戶創造了4,000個免費展位，深受澳門及大灣區居民和旅客歡迎，七年來累計吸引800,000人次入場。

今年展覽規模進一步擴大，場内設有逾580個特色展位，匯聚多個國際及本澳品牌，涵蓋家庭用品、食品美酒、美食廣場、文化創意、金沙商戶、澳門特色手信、兒童遊樂及運動體驗八大主題展區。

金沙中國有限公司行政副主席王英偉博士表示：「十分高興『金沙物美嘉年華』圓滿舉辦第七屆。七年過去，嘉年華由一項創新的中小企支援活動，逐步成長為澳門最大規模的消費品牌盛事，見證了無數中小微企的拼搏與成長，亦印證澳門社會同心同行的精神。多年來，活動助力本澳中小微企拓展商機，更為社服機構學員搭建實踐所學、展現潛能的舞台；凝聚工商界、社服界等力量，充分展現澳門多元活力。更令人欣喜的是，越來越多大灣區旅客因嘉年華相聚澳門，推動活動成為區內具影響力的消費盛事之一，七年來累計吸引80萬人次參與。衷心感謝澳門特別行政區政府以及社會各界多年來的支持與信任。未來，金沙中國將繼續發揮平台優勢，攜手本澳中小微企及社區夥伴開拓機遇、凝聚力量，持續為澳門經濟適度多元發展及『世界旅遊休閒中心』建設作出貢獻。」

今年活動注入多項新元素，包括打造歷來最大規模的「美食廣場」，匯聚58間澳門人氣食店，讓賓客感受本澳餐飲多元魅力；亦增設「運動體驗」展區，讓公眾投入匹克球的熱潮，並設有籃球投籃體驗，為今年十月在威尼斯人綜藝館強勢舉行的NBA中國賽預熱。此外，文化創意展區亦首度邀請到一眾來自粵港澳大灣區的文創品牌進駐。各特色展區人流絡繹不絕，氣氛熱烈，充分展現嘉年華的吸引力。

作為嘉年華的亮點活動之一，「工銀e支付呈獻：大灣區K歌之王歌唱比賽」一如既往反應熱烈，吸引近150名來自粵港澳大灣區的實力唱將報名參與，當中來自香港的參賽者佔總參賽人數逾半，反映活動已逐步輻射大灣區，吸引區內居民踴躍參與。賽事期間，一眾參賽者傾力獻唱，以精湛唱功及豐富舞台魅力掀起全場熱鬧氣氛。而專為公眾而設的「隨心所唱Busking Corner」專區亦吸引不少熱愛歌唱的人士即席表演，大會亦安排專業歌手進行暖場演出，進一步豐富嘉年華的活動體驗。

今年，金沙中國繼續聯動本澳多家社服機構參與嘉年華，為弱勢社群搭建展現才能及融入社會的平台。今屆共有20間社服機構參展，創歷屆新高，涵蓋社會復康、青年發展、動物權益及弱勢社群支援等範疇。活動讓有特殊教育需要人士及其他學員透過展銷親手製作的產品累積實踐經驗，提升技能與自信。公司同場亦舉辦連串社區關愛活動，進一步推動澳門共融社區發展。

活動每日更推出逾5,000件「1澳門元」精選產品及低至一折的優惠商品供入場人士選購。此外，嘉年華精心安排一系列親子活動。當中，備受歡迎的美食製作活動──「中銀Smart Kids呈獻：小廚神工作坊」今年載譽歸來，連同今年七年來共吸引近3,000人參與。今年，參加的親子家庭在金沙中國餐飲團隊的帶領下即場製作不同主題料理，盡享親子共廚樂趣。場內亦設有「交通銀行澳門分行呈獻：兒童遊樂專區」，提供充氣遊樂設施及攤位遊戲等精彩活動，讓小朋友盡情玩樂，同時促進親子互動。

「2026金沙物美嘉年華」由金沙中國主辦，澳門中華總商會協辦，並獲澳門特別行政區政府經濟及科技發展局、旅遊局及招商投資促進局大力支持；以及澳門中銀、工商澳門、交通銀行澳門分行及澳門大西洋銀行誠意贊助。

關於金沙中國有限公司

金沙中國有限公司（香港聯交所：1928，「金沙中國」或「公司」）是一所於開曼群島註冊成立的有限公司及在香港聯合交易所有限公司上市的公司。金沙中國是澳門最大的綜合度假村經營商，於路氹金光大道上設有澳門威尼斯人^®、澳門百利宮、澳門巴黎人^®，以及澳門倫敦人^® 等物業項目，同時擁有及經營位於澳門半島的澳門金沙。公司旗下的各綜合度假村集合多樣化的娛樂消閒、商務設施及客運業務，包括大型會議及展覽場地、各式餐廳食肆、購物中心、於威尼斯人綜藝館、倫敦人綜藝館、威尼斯人劇場、巴黎人劇場、倫敦人劇場及金沙劇場舉行的世界級娛樂表演，以及來往港澳的金光飛航高速渡輪服務。公司在路氹金光大道的各物業發展項目，堅定並持續地為建設澳門成為世界旅遊休閒中心貢獻力量。金沙中國是全球度假村發展商拉斯維加斯金沙集團股份有限公司（紐約證券交易所：LVS）的附屬公司。

如欲索取更多相關資訊，請瀏覽網頁https://hk.sandschina.com/index.html。

傳媒查詢：

金沙中國有限公司 – 企業傳訊部
胡美寶                                                                
電話：+853 8118 2268                                      
電郵：[email protected]              

鄭文軒
電話：+853 8118 2054
電郵：[email protected]

SHANGHAI, July 27, 2026 /PRNewswire/ -- Everest Medicines (HKEX 1952.HK, "Everest", or the "Company"), a biopharmaceutical company focused on the discovery, clinical development, manufacturing, and commercialization of innovative therapeutics, today announced that Ian Woo, President and Chief Financial Officer, will participate in the upcoming investor conferences.

Morgan Stanley Biotech Without Borders Series
Date: Tuesday, July 28, 2026
Time: US: 10:00am – 10:30am ET / 10:00pm – 10:30pm HKT
Format: Fireside chat
Webcast: https://morganstanley.webcasts.com/starthere.jsp?ei=1771095&tp_key=ca5039df5f

2nd Annual Evercore China Biotech Summit
Date: Tuesday, August 18, 2026
Time: 11:00am HKT
Format: Presentation and Q&A
Location: The Ritz-Carlton Shanghai, Pudong

About Everest Medicines

Everest Medicines is a biopharmaceutical company focused on discovering, developing, manufacturing and commercializing innovative pharmaceutical products that address critical unmet medical needs for patients in global markets. The management team of Everest Medicines has deep expertise and an extensive track record both in China and with leading global pharmaceutical companies. The Company's therapeutic areas of focus include autoimmune, ophthalmology, critical care, and CKM (cardiovascular, kidney, and metabolic) diseases. Everest Medicines has developed a fully integrated commercialization platform that combines omnichannel commercial capabilities with end-to-end product lifecycle management. Leveraging its proprietary mRNA platform, the Company is advancing its existing pipeline, including mRNA in vivo CAR-T and mRNA cancer vaccines, while selectively expanding into additional high-value therapeutic areas with blockbuster potential, and accelerating its global expansion. For more information, please visit the Company's website: www.everestmedicines.com.

Forward-Looking Statements
This news release may make statements that constitute forward-looking statements, including descriptions regarding the intent, belief or current expectations of the Company or its officers with respect to the business operations and financial condition of the Company, which can be identified by terminology such as "will," "expects", "anticipates", "future", "intends", "plans", "believes", "estimates", "confident" and similar statements. Such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, or other factors, some of which are beyond the control of the Company and are unforeseeable. Therefore, the actual results may differ from those in the forward-looking statements as a result of various factors and assumptions, such as future changes and developments in our business, competitive environment, political, economic, legal and social conditions. The Company or any of its affiliates, directors, officers, advisors or representatives has no obligation and does not undertake to revise forward-looking statements to reflect new information, future events or circumstances after the date of this news release, except as required by law.

上海2026年7月27日 /美通社/ -- 雲頂新耀（HKEX 1952.HK）是一家專注於創新藥研發、臨床開發、製造及商業化的生物製藥公司，今日宣佈總裁兼首席財務官何穎先生將出席以下即將舉行的投資者會議。

摩根士丹利 「Biotech Without Borders」 系列

日期: 2026年7月28日，週二
時間: 美東時間10:00am – 10:30am  / 北京時間10:00pm – 10:30pm 
形式：高管訪談（Fireside Chat）
網絡直播鏈接: https://morganstanley.webcasts.com/starthere.jsp?ei=1771095&tp_key=ca5039df5f
（僅向摩根士丹利海外客戶開放）

第二屆 Evercore 中國生物科技峰會

日期: 2026年8月18日，週二
時間: 北京時間11:00am 
形式: 演講及問答環節
地點: 上海浦東麗思卡爾頓酒店

關於雲頂新耀

雲頂新耀是一家專注於創新藥研發、臨床開發、製造和商業化的生物製藥公司，致力於滿足全球市場尚未滿足的醫療需求。雲頂新耀的管理團隊在中國及全球領先製藥企業擁有深厚的專長和豐富的經驗。公司在浙江嘉善擁有具備商業化規模的全球生產基地，並依據中國、美國及歐盟標準建立了完善的GMP生產質量管理體系。

公司聚焦自身免疫、眼科、急重症及CKM（心血管、腎臟及代謝）等疾病治療領域，已打造集全渠道商業化體系與藥品全生命週期商業化能力於一體的商業化平台，並以擁有全球權益的自研mRNA平台為基礎，持續推進mRNA in vivo CAR-T與mRNA腫瘤疫苗等現有管線，同時通過引進及生態孵化潛力平台，拓展研發能力，同時強化全球化佈局，加快國際化發展進程。更多信息，請訪問公司官網：www.everestmedicines.com。

前瞻性聲明

本新聞稿所發佈的信息中可能會包含某些前瞻性表述，乃基於本公司或管理層在做出表述時對公司業務運營情況及財務狀況的現有看法、相信、和現有預期，可能會使用「將」、「預期」、「預測」、「期望」、「打算」、「計劃」、「相信」、「預估」、「確信」及其他類似詞語進行表述。這些前瞻性表述並非對未來業績的保證，會受到風險、不確定性及其他因素的影響，有些乃超出本公司的控制範圍，難以預計。因此，受我們的業務、競爭環境、政治、經濟、法律和社會情況的未來變化及發展等各種因素及假設的影響，實際結果可能會與前瞻性表述所含資料有較大差別。本公司及各附屬公司、各位董事、管理人員、顧問及代理未曾且概不承擔更新該稿件所載前瞻性表述以反映在本新聞稿發佈日後最新信息、未來項目或情形的任何義務，除非法律要求。

成都2026年7月27日 /美通社/ -- 四川科倫博泰生物醫藥股份有限公司(「科倫博泰」或「公司」，6990.HK)宣佈，已收到國家藥品監督管理局(NMPA)藥品審評中心(CDE)同意新型雙載荷ADC藥物SKB565新藥臨床試驗(IND)申請的臨床試驗通知書，用於治療晚期實體瘤。這是公司首個進入臨床階段的雙載荷ADC。

SKB565基於公司專有的OptiDC™平臺開發，採用創新性雙載荷設計，可將毒素與免疫調節劑兩種具有協同作用機制的藥物直接遞送至腫瘤組織。相較于傳統僅搭載毒素的ADC藥物，SKB565具有雙重抗腫瘤機制：一方面能對腫瘤進行精准殺傷；另一方面可啟動腫瘤微環境的免疫系統，發揮抗腫瘤免疫反應，以實現更強和更持久的抑瘤效果。在臨床前研究中，SKB565展現出優異的抗腫瘤活性和安全性，其突出的腫瘤治療潛力為後續臨床開發提供了有力支撐。

憑藉在ADC領域的技術沉澱與平臺優勢，科倫博泰已佈局一系列結合高價值靶點、差異化設計並具備全球潛力的創新分子。在此基礎上，公司進一步拓展「ADC+IO」策略——一方面聚焦優質聯用療法的探索，包括正在開展臨床的多種ADC與PD-(L)1單抗聯合方案，以及PD-1/VEGF雙抗SKB118與公司眾多專有ADC資產的聯用；另一方面推進一體化策略研發，在單一ADC分子中整合具有協同作用機制功能元件。

科倫博泰首席執行官葛均友博士表示：「SKB565是我們『ADC+IO』一體化開發策略的核心代表藥物之一，可憑藉雙載荷的協同機制進一步強化療效、克服耐藥。當前，雙載荷ADC技術已是ADC領域的關鍵反覆運算方向之一，SKB565成功推進至臨床，不僅是公司技術平臺成果轉化的重要里程碑，亦證明了我們在ADC領域持續深化的自主創新能力。公司將積極推進SKB565等新型偶聯藥物的臨床開發，早日為腫瘤患者帶來更優獲益。」

關於科倫博泰

四川科倫博泰生物醫藥股份有限公司(簡稱「科倫博泰」，股票代碼：6990.HK)是科倫藥業控股子公司，專注于創新生物技術藥物及小分子藥物的研發、生產、商業化及國際合作。公司圍繞全球和中國未滿足的臨床需求，重點佈局腫瘤、自身免疫和代謝等重大疾病領域，建設國際化藥物研發與產業化平臺，致力於成為在創新藥物領域國際領先的企業。公司目前擁有30余個重點創新藥項目，其中4個項目8個適應症已獲批上市，1個專案處於NDA階段，10餘個專案正處於臨床階段。公司成功構建了享譽國際的專有ADC及新型偶聯藥物平臺OptiDC™，已有2個ADC項目5個適應症獲批上市，多個ADC或新型偶聯藥物產品處於臨床或臨床前研究階段。瞭解更多，請訪問： https://www.kelun-biotech.com/。

The beloved character makes its Southeast Asian debut as a POP MART Friend, with Dreamstar Isle and Southeast Asia's first POP BAKERY now open at Resorts World Sentosa

SINGAPORE, July 27, 2026 /PRNewswire/ -- Every star has a place where its story begins.

This summer, Twinkle Twinkle is embarking on a new journey across Southeast Asia, with Singapore chosen as its first stop in the region. Coinciding with the opening of POP MART's new Resorts World Sentosa store on 29 July, the visit marks Twinkle Twinkle's first appearance in Southeast Asia as a POP MART Friend and the beginning of a new chapter for the beloved little stars in the region.

At first, the little stars had only seen a faint glimmer from afar. Curious about where it came from, they followed it to Singapore — and discovered that the light was not coming from any single place.

It was found in the city's cultures, nature and everyday life, and in the smiles, hugs and unexpected connections shared with people along the way. What began as a brief first visit soon became something more: a wish to stay and keep discovering the many little lights that make Singapore shine.

Dreamstar Isle will become Twinkle Twinkle's first permanent home in Southeast Asia. Located within the new POP MART store at Resorts World Sentosa, Dreamstar Isle will give fans more opportunities to meet Twinkle Twinkle in person through regular POP MART Friend appearances, seasonal programmes and exclusive experiences throughout the year.

Southeast Asia's first POP BAKERY has also opened at the RWS store, bringing the world of Twinkle Twinkle to life through locally inspired themed desserts.

Following a Glimmer to the "Star Nation"

Ahead of the visit, POP MART released Twinkle Twinkle's official Singapore itinerary on 21 July, inviting fans to look out for the little stars at different locations across the city.

On 24 July, Twinkle Twinkle arrived at Changi Airport for its first appearance in Southeast Asia. Dozens of local fans gathered to welcome the rosy-cheeked little star, capturing its first moments in Singapore and greeting it with waves, high-fives and photos.

The warm airport reception became the first light Twinkle Twinkle found in Singapore, offering an early glimpse of the connection that would define its time in the city.

From Changi Airport, Twinkle Twinkle travelled across Singapore, strolling past the colourful shophouses of Joo Chiat and discovering the city's Peranakan heritage. It explored the underwater world of the Singapore Oceanarium, posed beside the Merlion and sampled local favourites at Lau Pa Sat.

Along the way, Twinkle Twinkle became more than the subject of a city photoshoot. It waved to passers-by, crossed paths with fans at local landmarks and brought people from different cultures and backgrounds together in shared moments of joy. Each encounter became another small light to remember.

For a group of little stars beginning their Southeast Asian journey, Singapore — affectionately known in Chinese as the "Star Nation" — felt like more than a fitting place to start. It seemed as though the distant glimmer had been leading them here all along.

One Glimmer Became a City Full of Light

Created by illustrator and designer Daxin in 2020, Twinkle Twinkle is a group of little stars, each with its own distinct personality. Innocent and curious, yet sometimes stubborn and endearingly clumsy, they tell stories of courage, love and longing. Through the characters, Daxin hopes everyone can recognise a little of themselves.

Singapore was originally meant to be only a brief first stop.

But somewhere between the warm welcome at Changi Airport and the unexpected encounters around the city, the colourful streets of Joo Chiat and the memories made beside the Merlion, Twinkle Twinkle began to understand the light it had seen from afar.

Singapore's light did not come from any single landmark. It was found in the city's open, multicultural spirit; in the wonder of the ocean and the flavours of Lau Pa Sat; and in every smile, wave and hug exchanged along the way.

The little stars decided to stay.

With the opening of POP MART Resorts World Sentosa, Singapore has become the first permanent home on Twinkle Twinkle's Southeast Asian journey. Dreamstar Isle gives the little stars a year-round home in the city, turning their first regional appearance into the beginning of an ongoing relationship with local fans.

A New Home at Dreamstar Isle

Located within the new POP MART store at Resorts World Sentosa, Dreamstar Isle is Twinkle Twinkle's first permanent home in Southeast Asia. It is a place where fans can meet the little stars through regular POP MART Friend appearances, seasonal programmes and exclusive experiences throughout the year.

Rather than marking a one-time visit, Dreamstar Isle creates an ongoing space for Twinkle Twinkle and its fans to meet again and again. It also serves as a starting point for the character to build deeper connections with Singapore and its local culture.

To celebrate the occasion, POP MART has introduced a new design bringing together Twinkle Twinkle and Singapore's Merlion, connecting the character with one of the city's most recognisable cultural symbols.

The RWS store is also home to Southeast Asia's first POP BAKERY. Originating from POP LAND, POP MART's theme park in Beijing, POP BAKERY brings characters to life through imaginative desserts, handcrafted drinks and immersive experiences.

For its Singapore debut, POP BAKERY has created Twinkle Twinkle-themed treats featuring locally inspired flavours, including coconut and sea salt. Together, the POP MART Friend appearances, localised designs and themed desserts offer fans new ways to experience the world of Twinkle Twinkle beyond its collectible products.

For Twinkle Twinkle, Dreamstar Isle is a place to continue discovering and remembering the little lights found across Singapore. For fans, it means their first meeting with the little stars will not be their last.

The Journey Continues

Singapore is the first stop on Twinkle Twinkle's Southeast Asian journey and the home of Dreamstar Isle — but it will certainly not be the last destination.

Twinkle Twinkle will continue travelling to more countries and cities, meeting new audiences through POP MART Friend appearances, local experiences and stories shaped by different cultures.

Every new place may reveal another light. Every encounter may become a story worth adding to the map.

In Singapore, the little stars followed one glimmer and found a city full of light.

Where will the next glimmer lead them?

About POP MART

Founded in 2010, POP MART (09992.HK) is a leading company in the designer collectibles and pop culture entertainment industry. Leveraging our ecosystem built around characters and IPs, connecting with our fans through creative, immersive experiences, POP MART aims to light up passion and bring joy to fans everywhere.

With a core focus on designer collectibles, theme parks & experiential services, and digital entertainment, we manage and represent exceptional artists globally. Our IP portfolio includes dozens of iconic characters loved by fans worldwide, such as THE MONSTERS, SKULLPANDA, CRYBABY, MOLLY, DIMOO, Twinkle Twinkle, and HIRONO. Our products are available in more than 90 countries and regions via 630+ stores, 2,600+ roboshops, and on major e-commerce platforms. The company went public on the Hong Kong Stock Exchange in 2020.