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2026-04-18
10:38
再鼎醫藥公布最新數據,顯示Zocilurtatug Pelitecan (Zoci) 在小細胞肺癌腦轉移患者中實現快速且顯著的顱內緩解,並在其他神經內分泌癌中展現出良好活性

  • Zoci,一款潛在同類首創的DLL3靶向抗體藥物偶聯物(ADC),在小細胞肺癌(SCLC)腦轉移患者中顯示出53.7%的確認顱內客觀緩解率(iORR);在1.6mg/kg劑量下,確認的iORR62.5%10/16),包括顱內腫瘤完全緩解的病例
  • 在肺外神經內分泌癌(NECs)中觀察到令人鼓舞的活性,經確認的客觀緩解率為38.2%
  • 針對二線及以上小細胞肺癌(SCLC)的全球3期研究正在進行中;一線SCLC和肺外神經內分泌癌項目將於2026年進入注冊性研究階段
  • 投資者電話會議和網絡直播將於420日(星期一)北京時間下午8:30(美國東部時間420日上午8:30/太平洋時間上午5:30)舉行,介紹在2026 AACR年會上公布的數據及後續臨床研究計劃

上海和馬薩諸塞州劍橋2026年4月18日 /美通社/ -- 再鼎醫藥有限公司(納斯達克股票代碼:ZLAB;香港聯交所股份代號:9688)今日宣布的臨床數據表明,靶向DLL3的ADC zocilurtatug pelitecan(zoci,前稱ZL-1310),在既往接受過治療的廣泛期小細胞肺癌(ES-SCLC)腦轉移患者中,經獨立評估采用改良版神經腫瘤腦轉移緩解評估(mRANO-BM)標准衡量,達到快速且顯著的顱內緩解,同時在其他神經內分泌癌(NECs)患者中顯示出有前景的數據。這些研究結果,以及ZL-6201(LRRC15 ADC)和ZL-1222(PD-1/IL-12)的臨床前數據,將在於聖地亞哥舉行的2026美國癌症研究協會(AACR)年會上公布。

一項正在進行的全球1期研究(NCT06179069)的結果表明,接受zoci治療可使腫瘤已轉移至大腦的ES-SCLC患者的顱內病灶顯著消退,該患者群體生存率低且缺乏有效治療選擇。

西班牙馬德裡12 de Octubre大學醫院腫瘤內科主任、西班牙國家癌症研究中心(CNIO)肺癌單元負責人Luis Paz-Ares博士表示:「對於發生腦轉移的廣泛期小細胞肺癌患者來說,腦轉移是導致疾病進展常見且具有重要臨床意義的驅動因素,其預後不佳,現有的治療方案不僅會延遲全身治療,且療效有限。正在進行的zoci的臨床數據令人鼓舞,不僅在多個劑量組中顯示出快速且顯著的緩解,而且無論患者既往是否接受過顱內放療,都顯示出顯著的活性。這些結果表明,zoci有望為治療選擇有限、難以治療的癌症提供一種新的治療選擇,滿足該患者群體未被滿足的巨大醫療需求。」

此外,研究人員還將分享一項zoci在肺外神經內分泌癌(epNEC)和其他選定實體瘤患者中的1b/2期臨床研究(NCT06885281)的初步數據。這些數據表明,zoci在這一類侵襲性強、預後差且治療選擇有限的惡性腫瘤患者群體中具有抗腫瘤活性,客觀緩解率(ORR)為38.2%。值得注意的是,目前經治的epNEC尚無獲批的標准治療方案。在這種癌症中也無靶向療法。

摘要標題:靶向DLL3ADC ZL-1310在經治的廣泛期小細胞肺癌伴基線腦轉移患者中的顱內活性:一項1期研究分析

該研究入組了伴有基線腦轉移的ES-SCLC患者,接受不同劑量(0.8、1.2、1.6、2、2.4或2.8 mg/kg)的zoci單藥治療,每三周靜脈給藥一次。數據的中位隨訪時間為7.9個月。全身性有效性采用研究者評估的RECIST v1.1標准,顱內有效性則由盲態獨立影像學委員會依據mRANO-BM來進行評估。

  • 在136名接受治療的患者中,36%在進入研究前的基線已存在腦轉移。
  • 在所有存在腦轉移且有機會完成至少兩次基線後掃描的患者中,接受zoci治療的患者顱內客觀緩解率(iORR)為53.7%(22/41),其中包括7例完全緩解。在1.6mg/kg劑量下,經確認的iORR為62.5%(10/16),包括4例完全緩解。14例患者在中位隨訪9.2個月時尚未出現進展或死亡事件(刪失)。
  • 多個劑量水平組均出現顱內腫瘤縮小,並且在既往接受過放療(50%,13/26)和未接受過放療(60%,9/15)的患者中均觀察到了緩解。
  • Zoci表現出可控的安全性特征,報告的大多數治療期出現的不良事件(TEAEs)為低級別,停藥極少。在總人群≥3級治療相關不良事件(TRAEs)發生率為19.9%(27/136),而接受1.6mg/kg劑量患者為16.4%(9/55)。最常見的≥3級TRAEs包括:中性粒細胞減少症(9.6%,13/136)、貧血(8.8%,12/136)、血小板減少症(3.7%,5/136)、淋巴細胞減少症(2.9%,4/136)、白細胞減少症(2.9%,4/136)。未報告顱內轉移並發症或治療相關的神經系統嚴重不良事件。

摘要標題:靶向DLL3ADC ZL-1310在神經內分泌癌和其他特定實體瘤患者中的1b/2期、開放標簽、多中心研究的初步結果

在另一項針對因侵襲性惡性腫瘤且治療選擇有限而存在高度未滿足需求的患者的重要分析中,zoci用於NECs患者的多中心1b/2期研究的初步結果顯示出具有臨床意義的緩解。研究人員以1.6mg/kg的劑量每三周靜脈注射一次zoci,直至疾病進展或出現不可接受的毒性,數據截止日期為2026年2月18日,研究1b期部分的中位隨訪時間為3.7個月。腫瘤反應由研究者根據RECIST v1.1標准評估,並對部分NECs進行了額外評估。

  • 在46名既往接受過鉑類化療和其他全身治療的患者中,zoci治療使多個肺外神經內分泌癌(epNEC)亞型的腫瘤體積縮小,且在經治患者中觀察到確認的緩解。
  • 在可評估緩解的患者中,所有研究隊列的總客觀緩解率為38.2%(13/34),總疾病控制率為55.9%(19/34)。
  • Zoci表現出可控的安全性特征;中性粒細胞計數下降(5.2%,3/58)是目前唯一在超過一名患者中發生的≥3級TRAE。

這些研究結果凸顯了zoci在多種表達DLL3的神經內分泌癌中的廣泛潛力。

再鼎醫藥總裁,全球研發負責人Rafael G. Amado博士表示:「我們將在AACR上公布的zoci數據,連同我們的ZL-6201和ZL-1222臨床前數據,共同凸顯了再鼎醫藥全球腫瘤研發管線的廣度、多樣性和潛力。Zoci快速進入關鍵性開發階段,計劃在今年年底前啟動三項注冊性研究,這是我們努力實現首個腫瘤產品全球上市戰略的印證。這一加速進展得益於我們獨特的中美一體化架構,使我們能夠聚焦速度和質量,將藥物發現轉化為改變生命的藥物。」

再鼎醫藥內部開發的另外兩款在研腫瘤療法的數據也將在AACR上公布。研究人員將分享ZL-6201(一款靶向富含亮氨酸重復序列蛋白15(LRRC15)的ADC,用於治療表達LRRC15的癌症相關成纖維細胞的肉瘤和上皮瘤)和ZL-1222(一種潛在的下一代抗PD-1/白細胞介素-12(IL-12)信號減弱突變體激動劑免疫細胞因子,用於癌症免疫治療)臨床前研究中令人鼓舞的發現。

網絡直播和電話會議的詳細信息如下: 
日期/時間:2026年4月20日,星期一,太平洋時間上午5:30 / 美國東部時間上午8:30 / 北京時間晚上8:30

注冊鏈接:
網絡直播(推薦)https://edge.media-server.com/mmc/p/8v9n78fj/
電話撥入: https://register-conf.media-server.com/register/BId10f18579c7947b29fda2857a99f26b9
演講人再鼎醫藥總裁,全球研發負責人Rafael G. Amado博士;西班牙馬德裡12 de Octubre大學醫院腫瘤內科主任、西班牙國家癌症研究中心(CNIO)肺癌單元負責人Luis Paz-Ares博士;紀念斯隆-凱特琳癌症中心胃腸腫瘤內科醫生Rohit Thummalapalli博士

關於Zocilurtatug Pelitecan (zoci, 前稱ZL-1310)

Zoci是一款靶向DLL3的新型ADC。DLL3是一種經過驗證的小細胞肺癌(SCLC)治療靶點,也在多種神經內分泌腫瘤中過度表達,通常與不良臨床預後相關。Zoci有望成為再鼎醫藥首個全球上市的抗腫瘤產品,計劃到2026年底開展三項注冊性研究,涉及二線及以上SCLC、一線SCLC以及肺外神經內分泌癌。Zoci具有潛在的同類最佳安全性特征,以及明確的全身性和顱內療效,支持其有望成為既往接受過治療的廣泛期小細胞肺癌(ES-SCLC)的新標准治療,並作為靶向DLL3的抗體偶聯藥物(ADC)基石,用於一線聯合治療方案,包括用以降低化療毒性負擔的治療方案,如聯合免疫檢查點抑制劑和T細胞銜接器。

關於ZL-6201

再鼎醫藥正在評估ZL-6201作為一款有望成為同類首創的靶向LRRC15抗體藥物偶聯物,用於治療多種實體瘤。LRRC15是一種I型跨膜蛋白,在多種間充質腫瘤(如肉瘤、膠質母細胞瘤和黑色素瘤)以及許多其他腫瘤類型的癌相關成纖維細胞中過度表達,是一個具有吸引力的癌症治療靶點。

關於ZL-1222

ZL-1222是一款潛在的新一代雙特異性免疫細胞因子,由抗PD-1抗體和抗體融合活性降低的IL-12組成,再鼎醫藥正在評估其用於多種適應證的癌症免疫治療,其有望在發揮強效抗腫瘤活性的同時改善全身安全性。此前,白介素-12療法已在多種癌症類型中顯示出潛在獲益,但狹窄的治療窗口和毒性問題限制了這類治療藥物的應用。

關於再鼎醫藥

再鼎醫藥(納斯達克股票代碼:ZLAB; 香港聯交所股份代號:9688)是一家以研發為基礎、處於商業化階段的創新型生物制藥公司,總部位於中國和美國。我們致力於通過創新產品的發現、開發和商業化解決腫瘤、免疫、神經科學和感染性疾病領域未被滿足的巨大醫療需求。我們的目標是利用我們的能力和資源為人類健康帶來積極影響。

有關再鼎醫藥的更多信息,請訪問www.zailaboratory.com或關注https://x.com/ZaiLab_Global

再鼎醫藥前瞻性聲明

本新聞稿包含關於再鼎醫藥未來預期、計劃和展望的前瞻性陳述,包括但不限於與我們開發和商業化zocilurtatug pelitecan (zoci)、ZL-6201和ZL-1222的前景和計劃、zoci、ZL-6201和ZL-1222的潛在獲益,以及小細胞肺癌、神經內分泌癌和實體瘤的潛在療法有關的陳述。本新聞稿中包含的所有陳述(對過往事實的陳述除外)均為前瞻性陳述,可以通過諸如「旨在」、「預計」、「認為」、「有可能」、「估計」、「預期」、「預測」、「目標」、「打算」、「可能」、「計劃」、「可能的」、「潛在」、「將會」、「將要」等詞匯和其他類似表述加以識別。該等陳述構成《1995年美國私人證券訴訟改革法案》中定義的「前瞻性陳述」。前瞻性陳述並非對未來表現的擔保或保證。前瞻性陳述基於我們截至本新聞稿發布之日的預期和假設,並且受到固有不確定性、風險以及可能與前瞻性陳述所預期的情況存在重大差異的情勢變更的影響。我們可能無法如我們在前瞻性陳述中所做出的披露實際實現計劃、執行意圖,或滿足期望或預測,您不應過分依賴該等前瞻性陳述。實際結果可能受各種重要因素的影響而與前瞻性陳述所示存在重大差異,該等因素包括但不限於:(1)我們成功商業化自身已獲批上市產品並從中產生收入的能力;(2)我們為自身的運營和業務活動獲取資金的能力;(3)我們候選產品的臨床開發和臨床前開發的結果;(4)相關監管機構對我們的候選產品作出審批決定的內容和時間;(5)與在中國營商有關的風險;和(6)我們向美國證券交易委員會(SEC)提交的最新年報和季報以及其他報告中指出的其他因素。我們預計後續事件和發展將導致我們的預期和假設改變,但除法律要求之外,不論是出於新信息、未來事件或其他原因,我們均無義務更新或修訂任何前瞻性陳述。該等前瞻性陳述不應被視為我們在本新聞稿發布之日後任何日期的意見而加以信賴。

如需查閱公司向SEC提交的文件,請訪問公司網站www.zailaboratory.com和SEC網站www.SEC.gov

Information Provided by PR Newswire [Disclaimer]
2026-04-17
22:13
Shanghai Electric Reports Strong 2025 Performance, New Orders Hit Record High

SHANGHAI, April 17, 2026 /PRNewswire/ -- Shanghai Electric (SEHK: 02727, SSE: 601727) announced its 2025 performance results, reporting revenue of RMB 126.68 billion (USD 18.58 billion), marking a 9.03% year-on-year increase. The net profit attributable to shareholders of the listed company reached RMB 1.206 billion (USD 176.92 million), a surge of 60.37% year-on-year. The total value of new orders received throughout the year amounted to RMB 172.81 billion (USD 25.35 billion), up 12.50% year-on-year, hitting a record high.

 

At the annual results briefing held on April 2 in Hong Kong, Shanghai Electric presented the company's 2025 performance and key financial data, while engaging with a wide range of institutional investors and analysts on business developments and future plans. The company delivered solid performance across core operating metrics in 2025, with notable improvements in overall business quality, driven by breakthroughs in new orders, technological innovation, and segment synergy.

Strong growth in profitability, new orders, and segment revenue

In 2025, Shanghai Electric achieved critical breakthroughs in emerging sectors, accelerated the execution and deployment of independent innovations in high-end manufacturing, and continued to deepen its global market presence.

The group's total operating profit reached RMB 5.02 billion (USD 736.73 million), up 34.28% year-on-year. Basic earnings per share stood at RMB 0.078, a significant increase of 62.50%.

The energy equipment segment generated revenue of RMB 75.02 billion (USD 11.01 billion), up 21.48% year-on-year, continuing to consolidate its industry leadership position.

Significant growth was achieved in the high-growth business sectors:

  • Wind power equipment orders reached RMB 22.966 billion (+32.18%, USD 3.37 billion);
  • Nuclear power equipment orders hit RMB 9.888 billion (+25.37%, USD 1.45 billion);
  • Gas power generation equipment orders amounted to RMB 3.095 billion (+33.35%, USD 454.04 million);
  • Power station service orders came in at RMB 7.312 billion (+45.28%, USD 1.07 billion).

Strengthened innovation capabilities and emerging sector breakthroughs

Shanghai Electric has achieved significant technological breakthroughs in new areas, including green methanol, green hydrogen, energy storage, and superconducting power, steadily improving its level of technological independence.

In high-end manufacturing, self-developed innovative products such as humanoid robots, industrial machine tools, and precision bearings are accelerating market application, further strengthening the company's core capabilities in this sector.

With research and development expenses reaching RMB 6.164 billion (USD 904.26 million) in 2025, Shanghai Electric's sustained high investment in R&D continues to underpin technological innovation and product upgrades.

Advancing industrial optimization and global market presence

In response to investor inquiries regarding its robotics deployment, aviation equipment business development, nuclear power equipment exports, coal-fired power tender outlook, and gas turbine exports, Shanghai Electric reaffirmed its commitment to further strengthening its position in energy equipment, enhancing the operational efficiency of industrial equipment, and expanding its global integrated service capabilities.

  • Traditional energy: to strengthen grid regulation capabilities and advance low-carbon upgrades, while accelerating the engineering deployment of nuclear power and nuclear fusion technologies.
  • High-end manufacturing: to scale up the development of robotics, aerospace equipment, and advanced machine tools, with a focus on achieving breakthroughs in key core technologies.
  • Overseas growth: to deepen its presence in overseas markets while enhancing its capabilities across desalination, power transmission and distribution, and energy equipment.

Executing 2026 priorities through innovation and digital transformation

In 2026, Shanghai Electric will continue to enhance core competitiveness with technological innovation as the primary engine, digital transformation as the main strategic direction, and green development as the foundation, to pursue high-end upgrades in traditional industries, scale up strategic emerging sectors, and make forward-looking moves in future industries.

Information Provided by PR Newswire [Disclaimer]
21:16
MGM Returns to Art Basel Hong Kong with an Immersive Showcase of Macau's Cultural-Tourism Landscape

Nurturing Arts Talent
Hong Kong–Macau Synergy Expands International Exchange Networks

HONG KONG, April 17, 2026 /PRNewswire/ -- MGM reaffirmed its long‑standing partnership with Art Basel Hong Kong this week, leading delegations of Macau cultural leaders, arts professionals, and university faculty and students to the fair for exclusive guided tours and dialogue sessions. The initiative aligns with the direction of China's "15th Five‑Year Plan", which calls for high‑quality cultural‑tourism development and advances the goal of helping Chinese culture go global. It also underscores the role of Hong Kong and Macau as key platforms for international cultural exchange.

The winner of the 2026 MGM Discoveries Art Prize is revealed with the award presented to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.
The winner of the 2026 MGM Discoveries Art Prize is revealed with the award presented to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.

As a pioneer in cultural‑tourism innovation, MGM has championed local arts development and talent cultivation for many years. Since forming a long‑term partnership with Art Basel Hong Kong in 2017, the Company has continued to build a bridge between Macau's arts community and the global stage, strengthening regional collaboration. This year, MGM once again served as a "super‑connector", drawing together artistic voices and cultural resources from Hong Kong and around the world. Encountering world‑class artworks at close range allowed participants to widen their global horizons, spark fresh ideas for Macau's arts development, and deepen the city's connection to international cultural networks.

This year, MGM also partnered with BOE, a global leader in display technology, to present an immersive showcase at its dedicated booth. The installation uses an "M‑shaped" four‑fold high‑definition, small‑pixel‑pitch LED display that combines intelligent energy efficiency with exceptional image clarity. Together with cutting‑edge naked‑eye 3D technology, it vividly brings to life a range of Macau's cultural‑tourism projects and highlights the diverse appeal of the city's integrated "culture + tourism + technology" development for the international arts community.

Cultivating a Fertile Environment for Macau's Arts Talent

Yesterday (March 26), MGM led a delegation of over 20 Macau cultural leaders, artists, and industry representatives to the VIP preview, where they engaged in in-depth exchanges with representatives from participating galleries. Today (March 27), MGM further welcomed 30 young local artists, arts students and faculty members to visit the fair and join the "Conversations" talks program, a signature highlight of Art Basel. They heard insights from renowned collectors and cultural leaders such as Saeb Eigner and Uli Sigg, exploring themes ranging from art collecting and cultural diplomacy to cross-regional exchange. The sessions deepened participants' understanding of Asian art development and the global arts ecosystem, while offering a close-up sense of the international art market's pulse.

MGM China Holdings Limited Chief Executive Officer and Executive Director Kenneth Xiaofeng Feng said: "MGM remains committed to leveraging Macau's unique role as a vital gateway for cultural exchange between East and West. Through our global network, we continue to create platforms that connect Macau's arts community with the world, helping industry professionals gain deeper insights into global art market trends and the practical dynamics of the art economy. We will continue strengthening our collaborations with the international cultural and arts sector, supporting Macau's moderate diversified economic development, and showcasing the city's immense potential in cultural‑tourism integration."

Zhu Jiao, who is currently pursuing a Doctor of Fine Arts at the University of Macau and participated in the exchange, said: "Having transitioned from MGM's National Arts Fund training program to attending Art Basel today, I can truly see how MGM continuously empowers young art professionals and students in Macau by building bridges to the global stage. These platforms allow us to immerse ourselves in the global art ecosystem and understand market dynamics firsthand. Such rare opportunities and valuable experiences are of great significance in broadening our creative horizons and helping us reflect on our future career development."

Cutting Edge Technology Animates Macau's Diverse Cultural Tourism Projects

MGM unveiled an innovative "M-shaped" four-fold high-definition, small-pixel-pitch LED display at the fair, using cutting-edge technology to break away from the limitations of traditional flat screens. The installation creates a sense of visual extension and a hyper-real, immersive virtual space, vividly re-creating precious artefacts from the "Silk Roads Beyond Borders" exhibition at the POLY MGM MUSEUM—including emblematic works such as the Blue-and-White Moon Flask with Strap Handles and the Dragon-Patterned Throne Carpet—alongside leading modern and contemporary artworks.

Highlights from MGM's resident production Macau 2049, which blends intangible cultural heritage with modern technology—including scenes such as "Khoomei: Ethereal"—are also brought to life on the screen. The booth further features looping promotional videos from the Macao SAR Government offering visitors an immersive glimpse into Macau's vibrant, innovative, and increasingly diversified cultural-tourism landscape.

2026 MGM Discoveries Art Prize Winner Announced

The winner of the 2026 MGM Discoveries Art Prize was also revealed today (March 27). After a rigorous selection process, the international jury awarded the prize to the artist of Galerie Allen in France, whose work stood out for its originality and forward-looking artistic vision.

Angelle Siyang-Le, Director of Art Basel Hong Kong, commented: "At Art Basel Hong Kong, we are committed to connecting artistic voices from Asia with the world and opening up meaningful exchanges across cultures. The MGM Discoveries Art Prize reflects a shared belief between Art Basel and MGM in supporting the next generation of artists and the galleries that stand behind them, while recognizing the originality and energy of emerging practices. We are especially pleased that the prize creates a meaningful opportunity for the winning artist and their gallery to engage with Macau through this rich cultural exchange."

Established jointly by MGM and Art Basel Hong Kong in 2025, the prize aims to identify and support promising emerging artists. The jury comprises five distinguished international arts and culture experts. The winning artist and their representing gallery receive a cash award and an invitation to visit Macau, where the artist will explore the city's unique East meets West cultural landscape, engage in creative exchange with local young artists, and potentially present their work in Macau.

About MGM

MGM is an abbreviation for MGM China Holdings Limited (HKEx: 2282) and is a leading developer, owner and operator of gaming and lodging resorts in Greater China. We are the holding company of MGM Grand Paradise, SA which holds one of the six gaming concessions to run casino games in Macau. MGM Grand Paradise, SA owns and operates MGM MACAU, the award-winning premium integrated resort located on the Macau Peninsula and MGM COTAI, a contemporary luxury integrated resort in Cotai. 

MGM MACAU is a Forbes Five-Star luxury integrated resort inspired by the arts with every element of the resort infused with creativity and style. MGM MACAU has approximately 600 guest rooms and suites and boasts a number of distinguishing features, including the architecturally stunning European-inspired Grande Praça, housed under a soaring glass ceiling. The POLY MGM MUSEUM spanning almost 2,000 square meters, is constructed in accordance with Chinese national standards for the exhibition of Grade-One cultural relics. MGM MACAU's world class facilities also include conference and event facilities, spa, and seven signature restaurants and bars to fulfill any gastronomic craving. Our property is conveniently located on the Macau Peninsula and is directly connected to the luxury retail shopping complex, One Central.

Designed as the "jewelry box" of Cotai, MGM COTAI offers approximately 1,400 hotel rooms and suites, meeting space, high end spa, retail offerings, food and beverage outlets as well as the first international Mansion at MGM for the ultimate luxury experience.  MGM has joined hands with renowned Chinese filmmaker Zhang Yimou to set up the "Macau 2049" residency in MGM Theater. The Spectacle at MGM COTAI becomes the record holder of the largest free-span gridshell glazed roof (self-supporting) on January 19, 2019, making it the first architectural and structural GUINNESS WORLD RECORDS™ title for Macau, China. MGM COTAI is being developed to drive greater product diversification and bring more advanced and innovative forms of entertainment to Macau as it grows as a global tourist destination. MGM COTAI is the only mega complex and hotel in Macau to gain three-star certification in both Green Building Design and Operation Label, as well as the first hotel in the Greater Bay Area and second in Greater China to receive the certifications.

MGM China is majority owned by MGM Resorts International (NYSE: MGM) one of the world's leading global hospitality companies, operating a portfolio of destination resort brands including Bellagio, ARIA, MGM Grand, Mandalay Bay and Park MGM. For more information about MGM Resorts International, visit the Company's website at www.mgmresorts.com.

About Art Basel

Founded in 1970 by gallerists from Basel, Art Basel today stages the world's premier art shows for Modern and contemporary art, sited in Basel, Miami Beach, Hong Kong, Paris, and Qatar. Defined by its host city and region, each show is unique, which is reflected in its participating galleries, artworks presented, and the content of parallel programming produced in collaboration with local institutions for each edition. Art Basel's engagement has expanded through new digital platforms including Zero 10 and the Art Basel App, and initiatives such as the Art Basel and UBS Global Art Market Report and Survey of Global Collecting, Art Basel Awards, and Art Basel Shop. For further information, please visit artbasel.com.

Information Provided by PR Newswire [Disclaimer]
21:15
XPENG to Showcase "Physical AI" Ecosystem at Beijing Auto Show, Outlining Global Vision for Smart Mobility

BEIJING, April 17, 2026 /PRNewswire/ -- XPENG will unveil its next-generation "Physical AI" ecosystem at the Beijing Auto Show starting April 24, showcasing its transition from a smart EV manufacturer to a global leader in physical AI. The presentation will feature a comprehensive portfolio spanning intelligent driving, robotics, and aerial mobility, alongside the latest technical and product updates.

2026 marks a milestone as Physical AI enters mass production. At the Auto Show, XPENG will showcase the VLA 2.0 intelligent driving system, flagship models, as well as the latest progress in robotics and flying cars. The VLA 2.0 is redefining how users perceive smart driving, with positive feedback rising, higher model conversion rates, and growing adoption of the Ultra version. The recently launched Mona UltraSE version broadens access to advanced intelligent driving, allowing a younger, wider audience to experience the benefits of  VLA 2.0 technology. Visitors will have the opportunity to engage with key VLA features, including autonomous campus roaming, fully automated parking, and advanced urban navigation.

XPENG now operates in over 60 countries and regions globally. In 2025, the company delivered 45,000 vehicles abroad—a 95.6% increase year-on-year—continuing to lead the international expansion of Chinese EVs. The Beijing Auto Show 2026 will mark a significant step in this journey, offering media, partners, and consumers a first-hand look at the future of smart mobility.

About XPENG

Founded in 2014, XPENG is a leading AI-driven mobility company that designs, develops, manufactures, and markets Smart EVs, catering to a growing base of tech-savvy consumers. With the rapid advancement of AI, XPENG aspires to become a global leader in AI mobility, with a mission to drive the Smart EV revolution through cutting-edge technology, shaping the future of mobility. To enhance the customer experience, XPENG develops its full-stack advanced driver-assistance system (ADAS) technology and intelligent in-car operating system in-house, along with core vehicle systems such as the powertrain and electrical/electronic architecture (EEA). Headquartered in Guangzhou, China, XPENG also operates key offices in Beijing, Shanghai, Silicon Valley, and Amsterdam. Its Smart EVs are primarily manufactured at its facilities in Zhaoqing and Guangzhou, Guangdong province.

XPENG is listed at the New York Stock Exchange (NYSE: XPEV) and Hong Kong Exchange (HKEX: 9868).

Contacts:

For VLA test drive requests or other media inquiries, please contact the XPENG PR Department via the following channels:

Email: [email protected]

Website: https://www.xpeng.com

Information Provided by PR Newswire [Disclaimer]
21:02
美高梅再度亮相巴塞爾藝術展 立體躍現澳門文旅圖景

培育藝術人才 港澳聯動拓展國際交流網絡

澳門2026年4月17日 /美通社/ -- 美高梅作為文旅領航者,多年來積極支持本地藝術發展及人才培育,自2017年與巴塞爾藝術展香港展會建立長期合作夥伴關係以來,持續為澳門藝術社群搭建接軌國際的平台,促進區域合作。為響應國家「十五五」規劃中推動文旅產業高質量發展、打造港澳成為中華文化出海及國際交流高地之戰略方向,美高梅持續發揮「超級聯繫人」角色,聯動香港及國際藝文資源,今年再度邀請澳門文化界領袖、藝術從業者及高校師生前往展會,參與專屬導覽及座談活動。與會者藉由親炙國際級藝術佳作,既拓闊全球化及前瞻性的文化視野,為澳門藝術發展注入創新思維,也拓展本地藝術生態與國際網絡的深度連結。

同時,美高梅今年與全球領先的顯示技術企業京東方(BOE)合作,於展會現場的美高梅專屬展位,透過兼具智慧節能與極緻畫質的「M」形四折結構高清小間距LED顯示屏及前沿的裸眼3D顯示技術,生動呈現澳門多項文旅項目內容,向國際藝術界展現澳門「文化+旅遊+科技」融合發展的多元魅力。

厚植澳門藝術人才發展沃土
美高梅於昨日(26日)率先帶領逾20位澳門文化界領袖、藝術家及業界代表等參與預展專場,並與各藝廊代表深入交流;今日(27日),則進一步邀請30位本澳年輕藝術工作者和藝術專業的高校師生參觀展會並參加展會的重要交流項目「與巴塞爾藝術展對話」系列座談活動,聆聽賽義卜.艾格納(Saeb Eigner)、烏利.希克(Uli Sigg)等知名收藏家及藝術界領袖的分享,從藝術收藏、文化外交到跨地域交流等多重角度,深化對亞洲藝術發展脈絡及國際藝文生態的理解,近距離感受環球藝術市場脈動。

美高梅中國控股有限公司首席執行官及執行董事馮小峰表示:「美高梅始終致力發揮澳門作為中西文化交流重要窗口的獨特優勢,憑藉品牌獨有的國際網絡,持續為本澳藝文界搭建聯通世界的平台,助力業界加深了解環球藝術市場趨勢及藝術經濟發展實務,進一步拓寬發展空間。我們將繼續深化與全球文化藝術領域的交流合作,助力澳門經濟適度多元發展,並向世界展現澳門文旅融合發展的豐沛潛力。」

參與是次交流的澳門大學藝術博士學位課程在讀生朱姣表示:「從早前參加美高梅主辦的國家藝術基金人才資助項目課程,到今日獲邀參觀巴塞爾藝術展,我深刻感受到美高梅一直持續為本澳青年藝術人才及藝術專業學生提供多元化交流平台,讓我們有機會接觸國際藝壇、並深入了解全球藝術生態與市場脈動。這些難得的機會與寶貴的經驗,對我們拓寬創作視野與思考未來職業規劃都具有重要的意義。」

嶄新科技活現澳門多元文旅項目
美高梅以創新的「M」形四折結構高清小間距LED顯示屏亮相展會現場,運用前沿科技打破傳統平面的視覺局限,形成視覺延伸,構造出觸手可及的現實感虛擬空間,生動還原保利美高梅博物館「絲路」大展中的珍貴展品,包括青花輪花紋綬帶耳葫蘆瓶、龍紋寶座毯等代表性文物,以及現當代頂級藝術品。同時,美高梅駐場鉅製《澳門2049》融合非物質文化遺產與現代科技的精華段落——如「呼麥•飄渺」等場景,也在屏幕上震撼重現。現場還循環展播澳門特別行政區政府宣傳片,讓觀眾身臨其境,感受澳門文旅產業多元融合、創新發展的嶄新氣象。

2026年度「美高梅藝術探新獎」得主揭曉
此外,2026年度「美高梅藝術探新獎」亦於今日(27日)揭曉。國際評審團經嚴謹評選後,由法國畫廊Galerie Allen帶來的藝術家憑藉其作品展現出的前瞻性與原創性,從一眾國際新銳藝術家中脫穎而出。

巴塞爾藝術展香港展會總監樂思洋表示:「巴塞爾藝術展香港展會一直致力連結亞洲與世界各地藝術界,促進跨文化間富有意義的交流與對話。『美高梅藝術探新獎』體現了雙方的共同理念,支持新一代藝術家及其畫廊,並肯定新晉藝術創作所展現的原創性與活力。我們亦樂見此獎項為得獎藝術家及其畫廊提供與澳門交流的機會,透過這段極具意義的文化交流,開拓新的創作靈感與發展方向。」

該獎項由美高梅與巴塞爾藝術展香港展會於2025年共同設立,旨在發掘並支持具潛力的藝術新秀。評審團由五位資深國際藝術文化專家組成,獲獎藝術家與其代理藝廊共同獲得獎金,並獲邀前往澳門,以藝術視角探索澳門中西文化交融的獨特魅力,與當地青年人才交流,啟發更多創意靈感,更有機會在澳門展出作品。

更多高清相片:HK Press Kit

2026年度「美高梅藝術探新獎」由法國畫廊Galerie Allen帶來的藝術家憑藉其作品展現出的前瞻性與原創性,從一眾國際新銳藝術家中脫穎而出。
2026年度「美高梅藝術探新獎」由法國畫廊Galerie Allen帶來的藝術家憑藉其作品展現出的前瞻性與原創性,從一眾國際新銳藝術家中脫穎而出。

關於美高梅

美高梅中國控股有限公司(股份代號:2282)簡稱美高梅,為大中華地區領先的娛樂場博彩度假酒店發展商、擁有者和運營商之一,是美高梅金殿超濠股份有限公司的控股公司,為六家持有澳門經營博彩業務特許權的企業之一。美高梅金殿超濠現時擁有及經營兩家酒店:澳門美高梅位於澳門半島、是屢獲殊榮的豪華綜合度假酒店;而位於澳門路氹城的美獅美高梅為一現代豪華綜合度假酒店。

澳門美高梅是《福布斯旅遊指南》五星評級之綜合度假酒店,是一充滿創意和風格的藝術傑作。除了約600間豪華客房及套房,賓客還能在這裏發現眾多與別不同的奢華享受,包括以巨型玻璃天幕覆蓋、充滿歐陸設計特色的天幕廣場,氣勢磅礡。澳門美高梅擁有世界一流的設施,包括面積近2,000平方米按照國家一級文物展陳標準建造的博物館 —「保利美高梅博物館」、水療中心、七間各具特色且集合各國佳餚的餐廳及酒吧等,而功能齊全的會議及場地設施,也讓澳門美高梅成為舉辦各類宴會的理想地點。酒店位於澳門半島最矚目的地段上,位置優越,與名店林立的壹號廣塲相連。

美獅美高梅設計猶如路氹城的「珠寶盒」,設有約1,400間客房及套房、偌大的會議空間、奢華的水療設施、零售商店、餐飲配套、美高梅首間國際酒店別墅「雍華府」,及上演美高梅與中國大導演張藝謀攜手打造《澳門2049》駐場秀的美高梅劇院。美獅美高梅的視博廣場天幕在2019年1月19日被評為最大的懸跨網架式結構玻璃屋頂(自支撐),是中國澳門首個建築及結構範疇的健力士世界紀錄™榮譽。美獅美高梅旨在推動多元化發展,為澳門帶來更多元及創新的娛樂體驗,讓澳門繼續發展成為世界旅遊休閒中心。美獅美高梅是澳門唯一囊括三星級綠色建築設計標識和運行標識的巨型綜合建築及酒店,更是大灣區首家及大中華區第二家取得該認證的酒店。

美高梅中國控股有限公司主要由美高梅國際酒店集團(MGM Resorts International)擁有(紐約證券交易所代號:MGM)。美高梅國際酒店集團是世界領先的全球酒店及餐飲款待公司,其轄下的度假酒店項目包括百樂宮大酒店(Bellagio)、亞利亞(ARIA)、美高梅大酒店(MGM Grand)、曼德拉灣大酒店(Mandalay Bay)及Park MGM。有關美高梅國際酒店集團的詳情,請瀏覽 www.mgmresorts.com

關於巴塞爾藝術展

巴塞爾藝術展於1970年由巴塞爾的藝廊創辦人成立,現今為全球頂尖的現當代藝術展會,每年於巴塞爾、邁阿密海灘、香港、巴黎及多哈舉行。每個展會均因各自的城市與地域而別具特色,具體體現在參展藝廊、展出作品,以及與當地文化機構為每屆展會合作策劃的同期活動內容之中。通過諸如「Zero 10」項目與巴塞爾藝術展應用程式等數碼平台,以及《巴塞爾藝術展與瑞銀集團環球藝術市場報告》、《巴塞爾藝術展與瑞銀集團環球藝術收藏調查報告》、巴塞爾藝術獎(Art Basel Awards)及巴塞爾藝術展商店等項目,巴塞爾藝術展將自身影響力拓展至藝術展會之外。獲取更多信息,請訪問 artbasel.com

Information Provided by PR Newswire [Disclaimer]
19:43
ZTO Express to Hold Annual General Meeting on June 16, 2026

SHANGHAI, April 17, 2026  /PRNewswire/ -- ZTO Express (Cayman) Inc. (NYSE: ZTO and HKEX: 2057) ("ZTO" or the "Company"), a leading and fast-growing express delivery company in China, today announced that it will hold its annual general meeting of shareholders ("AGM") on Tuesday, June 16, 2026, at 2:00 p.m. (Hong Kong time), at 9/F, The Center, 99 Queen's Road Central, Central, Hong Kong, for the purposes of considering and, if thought fit, passing each of the Proposed Resolutions as defined and set forth in the notice of the AGM (the "AGM Notice"). An online live webcast of the meeting will also be made available for holders of ordinary shares of the Company as of the Record Date. The AGM Notice and the form of proxy for the AGM are available on the Company's website at http://zto.investorroom.com. The board of directors of the Company fully supports the Proposed Resolutions and recommends that shareholders and holders of American depositary shares ("ADSs") vote in favor of the Proposed Resolutions.

Holders of record of ordinary shares of the Company at the close of business on May 8, 2026, Hong Kong time (the "Record Date"), are entitled to notice of and to attend and vote at the AGM or any adjournment or postponement thereof. Holders of record of ADSs as of the close of business on May 8, 2026, New York time, who wish to exercise their voting rights for the underlying Class A ordinary shares must give voting instructions to JPMorgan Chase Bank, N.A., the depositary of the ADSs.

You may obtain an electronic copy of the Company's annual report, free of charge, from the Company's website at http://zto.investorroom.com, The Stock Exchange of Hong Kong Limited's website at www.hkexnews.hk or from the U.S. Securities and Exchange Commission's website at www.sec.gov

About ZTO Express (Cayman) Inc.

ZTO Express (Cayman) Inc. (NYSE: ZTO and SEHK: 2057) ("ZTO" or the "Company") is a leading and fast-growing express delivery company in China. ZTO provides express delivery service as well as other value-added logistics services through its extensive and reliable nationwide network coverage in China.

ZTO operates a highly scalable network partner model, which the Company believes is best suited to support the significant growth of e-commerce in China. The Company leverages its network partners to provide pickup and last-mile delivery services, while controlling the mission-critical line-haul transportation and sorting network within the express delivery service value chain.

For more information, please visit http://zto.investorroom.com

For investor inquiries, please contact:

ZTO Express (Cayman) Inc.
Investor Relations
E-mail: [email protected]
Phone: +86 21 5980 4508

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19:30
Tencent Music Entertainment Group Filed 2025 Annual Report on Form 20-F

SHENZHEN, China, April 17, 2026 /PRNewswire/ -- Tencent Music Entertainment Group ("TME", or the "Company") (NYSE: TME and HKEX: 1698), the leading online music and audio entertainment platform in China, today announced that it has filed its annual report on Form 20-F that includes its audited financial statements for the fiscal year ended December 31, 2025 with the Securities and Exchange Commission (the "SEC") on April 17, 2026, U. S. Eastern Time.

The annual report can be accessed on TME's investor relations website at ir.tencentmusic.com and on the SEC's website at www.sec.gov. The Company will also provide a hard copy of the annual report containing its audited consolidated financial statements, free of charge, to its shareholders and American Depositary Share holders upon request.

About Tencent Music Entertainment

Tencent Music Entertainment Group (NYSE: TME and HKEX: 1698) is the leading online music and audio entertainment platform in China, operating the country's highly popular and innovative music apps: QQ Music, Kugou Music, Kuwo Music and WeSing. TME's mission is to create endless possibilities with music and technology. TME's platform comprises online music, online audio, online karaoke, music-centric live streaming and online concert services, enabling music fans to discover, listen, sing, watch, perform and socialize around music. For more information, please visit ir.tencentmusic.com.

Investor Relations Contact
Tencent Music Entertainment Group
[email protected]
+86 (755) 8601-3388 ext. 885034

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19:28
ZTO Files Annual Report on Form 20-F for Fiscal Year 2025

SHANGHAI, April 17, 2026 /PRNewswire/ --  ZTO Express (Cayman) Inc. (NYSE: ZTO and HKEX: 2057), a leading and fast-growing express delivery company in China ("ZTO" or the "Company"), today announced that it filed its annual report on Form 20-F for the fiscal year ended December 31, 2025 with the U.S. Securities and Exchange Commission ("SEC") on April 17, 2026. The annual report on Form 20-F can be accessed on the Company's investor relations website at http://zto.investorroom.com as well as the SEC's website at http://www.sec.gov

The Company will provide a hard copy of its annual report on Form 20-F containing the audited consolidated financial statements, free of charge, to its shareholders upon request. Requests should be directed to the Company's IR Department at [email protected]

The Company has also today published its annual report for the fiscal year ended December 31, 2025 pursuant to the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited ("HKEX"), which can be accessed on the Company's investor relations website at http://zto.investorroom.com as well as the HKEX's website at http://www.hkexnews.hk

About ZTO Express (Cayman) Inc.

ZTO is a leading and fast-growing express delivery company in China. ZTO provides express delivery service as well as other value-added logistics services through its extensive and reliable nationwide network coverage in China.

ZTO operates a highly scalable network partner model, which the Company believes is best suited to support the significant growth of e-commerce in China. The Company leverages its network partners to provide pickup and last-mile delivery services, while controlling the mission-critical line-haul transportation and sorting network within the express delivery service value chain.

For more information, please visit http://zto.investorroom.com

For investor and media inquiries, please contact:

ZTO Express (Cayman) Inc.

Investor Relations

E-mail: [email protected]
Phone: +86 21 5980 4508

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18:30
以責任賦能發展 以初心傳遞溫度 ---- 中通快遞正式發佈 2025 年度可持續發展報告

上海2026年4月17日 /美通社/ -- 2026年4月17日,中國行業領先且快速成長的快遞公司中通快遞(開曼)有限公司(紐交所代碼:ZTO及香港聯交所代號:2057)(「中通」或「公司」)正式發佈了2025年度可持續發展報告。這是公司連續第九年發佈可持續發展專項報告,標誌著中通實現從 「履責披露」 向 「價值創造」 的升級轉型,以系統化、國際化、戰略化視角,全面展現企業可持續發展實踐成果與長遠佈局。

賴梅松董事長在報告致辭中表示:「2025 年是『十四五』規劃收官之年,郵政快遞業高質量發展續寫新篇。回望這一年,中通始終堅守長期主義,堅持黨建引領與經營發展深度融合,將企業發展深度融入國家戰略與民生所需,以『同建共享』為根基、以『實幹奮鬥』為底色,交出了一份兼具規模、韌性與責任的答卷。我們始終堅信,可持續發展從來不是企業發展的『附加題』,而是邁向高質量發展的『必答題』,更是我們踐行『用我們的產品造就更多人幸福』企業使命、實現『利他利社會』的核心路徑。」

「展望『十五五』新征程,中通將全面貫徹落實國家郵政局『兩促進、三提升』的工作要求,圍繞『重安全、強服務,真調優、增效益,建公平、聚人心,強執行、挖潛力』的工作主線,持續做強三條增長曲線,堅守自律發展、以人為本、利他利社會的初心,與各界夥伴攜手同行,在服務美好生活的進程中,走得更穩、更遠、更有溫度!」

持續深耕 ESG 體系建設以來,中通綜合治理能力與國際認可度穩步提升,多項主流國際 ESG 評級持續優化,行業排位穩步前移。憑藉穩健經營與紮實的責任實踐,公司年內斬獲多項國家級、行業級重磅榮譽,品牌價值與社會影響力持續躍升。

在綠色低碳領域,中通持續完善全鏈路綠色物流體系建設,穩步推進清潔能源佈局與末端綠色配送升級。通過光伏項目規模化落地、無人配送車隊廣泛普及、低碳運營模式推廣等多元舉措,有效降低全鏈路碳排放,多項綠色實踐入選行業優秀典型案例,助力物流行業綠色低碳轉型。

在數智創新與服務升級方面,中通以科技賦能全鏈路提質增效,持續強化末端履約能力與差異化服務水平。依託大數據、人工智能等技術優勢,不斷優化全網運營效率;持續下沉鄉村物流網絡,深化快遞與製造業融合發展,切實服務實體經濟與城鄉民生流通。

員工關懷與網點共生層面,中通始終堅持以人為本,完善一線勞動者權益保障與暖心幫扶機制,常態化開展關懷保障活動,切實提升從業人員歸屬感與幸福感。同時,全方位推進網點賦能計劃,通過多元舉措強化末端經營韌性,穩定產業鏈供應鏈生態。

立足社會公益,中通積極踐行企業社會責任,持續加大公益投入,深耕愛心助學、助殘幫扶、慈善捐贈等公益領域,長期落地多項特色公益項目,以長效、務實的公益行動回饋社會,傳遞企業溫暖力量。

治理合規方面,中通持續優化可持續發展頂層設計,完善專項治理架構,健全考核激勵機制。從嚴抓實內控管理、信息安全與廉潔合規建設,全方位築牢經營風險防線,以規範化、現代化治理,護航企業高質量長遠發展。

以上為本次報告的核心內容摘要。如需了解公司2025年度可持續發展的完整戰略佈局、具體實踐與階段性成果,敬請查閱官方完整版可持續發展報告: https://zto.investorroom.com/ESG

關於中通快遞(開曼)有限公司

中通快遞(開曼)有限公司是中國行業領先且快速成長的快遞公司。中通通過其在中國廣泛且可靠的全國性覆蓋網絡提供快遞服務以及其他增值物流服務。

中通運營高度可擴展的網絡合作夥伴模式,本公司認為,該模式最適於支援中國電子商務的高速增長。本公司利用其網絡合作夥伴提供攬件和末端派送服務,同時在快遞服務價值鏈內提供關鍵的幹線運輸服務和分揀網絡。

有關更多資料,請訪問 http://zto.investorroom.com

安全港聲明

本公告包含可能根據1995年美國《私人證券訴訟改革法案》的「安全港」規定項下作出的「前瞻性」陳述。這些前瞻性陳述可以通過諸如「將會」、「期望」、「預期」、「旨在」、「未來」、「打算」、「計劃」、「相信」、「估計」、「可能」等術語和類似聲明來識別。中通亦可能在其向美國證券交易委員會(「美國證交會」)及香港聯合交易所有限公司(「香港聯交所」)提交的定期報告、向股東提交的中期及年度報告、於香港聯交所網站上發佈的公告、通函或其他刊物、新聞稿及其他書面材料以及其高級職員、董事或僱員向第三方作出的口頭陳述中作出書面或口頭前瞻性陳述。非歷史事實的陳述,包括有關中通的信念、計劃和期望的陳述,均為前瞻性陳述。前瞻性陳述涉及固有風險和不確定性。許多因素可導致實際結果與任何前瞻性聲明中包含的結果有重大差異,包括但不限於以下各項:有關中國電子商務及快遞行業發展的風險;其對若干第三方電子商務平台的重大依賴;與其網絡合作夥伴及其僱員及人員相關的風險;可能對本公司經營業績及市場份額造成不利影響的激烈競爭;本公司分揀中心或其網絡合作夥伴運營的網點或其技術系統遭受任何服務中斷;中通建立品牌及承受負面報道的能力或其他有利的政府政策。有關此等及其他風險的進一步資料載於中通向美國證交會及香港聯交所提交的文件中。本公告中提供的所有信息均截至本公告發佈之日,除適用法律要求的範圍外,中通不承擔任何更新前瞻性陳述的義務。

投資者及媒體諮詢請聯繫:
中通快遞(開曼)有限公司
投資者關係
電郵:[email protected] 
電話:+86 21 5980 4508

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09:00
Tesla Weighs Producing Humanoid Robots at Shanghai Gigafactory

Tesla (TSLA.US) is considering producing humanoid robots at its Shanghai Gigafactory to maintain its growth in the mainland market, targeting an annual production capacity of 100,000 units by the end of this year, Chinese media reported.

Wang Hao, Vice President of Tesla and President of Tesla China, said that the Shanghai Gigafactory, like Tesla's other factories, will undertake an extremely pivotal role as a production base, with the arrival of the robotics era. However, Tesla has not yet disclosed specific details regarding the production launch timeline and scale.
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