Completing 2G Service Cessation and Advancing to 5.5G Intelligent Communications

HONG KONG, June 23, 2026 /PRNewswire/ -- China Mobile Hong Kong Company Limited ("CMHK") today announced, with the approval of the Communications Authority ("CA"), the official cessation of its second-generation mobile communications ("2G") service. This milestone marks CMHK as the first mobile network operator in Hong Kong to provide only 4G, 5G and 5.5G high-speed mobile communications services, underscoring the Company's continued commitment to building a more efficient, intelligent and future-ready mobile network in Hong Kong.

Driving the continuous advancement of network technology

CMHK remains committed to the advancement of network technology and continuous enhancement of its network infrastructure and service capabilities. Following the cessation of its 3G service in June 2025, the completion of 2G service cessation today marks another significant milestone in the Company's network evolution. Valuable spectrum resources and related technologies will be reallocated to the development of 5G and 5.5G networks, further enhancing network capacity, coverage efficiency and intelligent management. This will bring customers a faster, lower-latency and more stable mobile communications experience, while supporting the rapid development of AI applications, the IoT, industry digitalization and smart city innovation. It will also establish a solid foundation for the long-term development of Hong Kong's network infrastructure and information technology ecosystem.

AI Technology Empowers Network Upgrade

During this network upgrade, CMHK made full use of AI technologies to optimize the entire transition process. Through big data analytics and machine learning models, the Company accurately identified 2G users and engaged them through intelligent outbound calls, SMS messages and app reminders, achieving cumulative customer reach of more than 8 million touchpoints.

In addition, CMHK leveraged its self-developed AI-powered intelligent network to help teams rapidly identify terminal compatibility and potential service needs, significantly enhancing customer service and support efficiency. Together with real-time monitoring of network quality and user experience, overall network performance remained stable throughout the process, enabling a smooth technology transition with minimal impact on customers.

Caring Support and Social Responsibility

CMHK remains committed to balancing technology advancement with social responsibility, and has established a comprehensive customer support system to ensure a smooth transition. For elderly customers using legacy devices, the Company proactively provided one-on-one on-site and remote assistance, large-print user guides, dedicated hotlines and priority service channels at retail stores, ensuring a worry-free and seamless transition for customers. The Company also introduced dedicated subsidies to support customers in replacing legacy devices, and offered free replacement of next-generation USIM cards. In addition, written notifications were sent by registered mail, while terminal device subsidies have been extended to 31 December 2026, ensuring a seamless upgrade of customers' communications experience.

The completion of 2G service cessation marks the fulfilment of a historic mission in the development of mobile communications. It also marks Hong Kong's mobile network entering a new stage of greater efficiency, intelligence and innovation. Looking ahead, CMHK will continue to focus on the core development of 5.5G, while further investing in innovative technology research and development, AI-powered network intelligence and smart city infrastructure. The Company will continue to empower the digital transformation of industries and support Hong Kong in developing into an international innovation and technology hub with global influence.

About China Mobile Hong Kong Limited

China Mobile Hong Kong Company Limited ("CMHK") is the wholly-owned subsidiary of China Mobile Limited (HKEx: 941), which is listed on the Fortune Global 500. CMHK was incepted in January 1997 and was the first mobile network operator to launch PCS services in Hong Kong.

As the world's leading mobile network brand with the largest customer base*, The Company offers innovative and comprehensive 5G communications services, including voice, data, IDD and international roaming. The Company is committed to the development of 5G with new technologies such as artificial intelligence, internet of things, cloud computing and big data, integrating 5G applications in different industries, promoting the construction and development of smart city groups in Greater Bay Area.

* China Mobile (Hong Kong) Limited is a wholly-owned subsidiary of China Mobile Limited. As of 31 December 2025, China Mobile Limited had the largest number of mobile network subscribers in the world.

完成2G網絡技術迭代  邁步5.5G智慧通訊新里程

香港2026年6月23日 /美通社/ -- 中國移動香港有限公司（簡稱「中國移動香港」）宣佈，經通訊事務管理局（通訊局）批准，已於今天正式完成第二代流動通訊（2G）退網工作，是全港首家僅提供4G / 5G / 5.5G高速流動通訊服務的營運商，標誌香港流動通訊邁向更高效、更智能的新階段。

推動網絡技術與時並進
中國移動香港一直積極推動網絡技術升級，持續優化網絡基建與服務能力。繼2025年 6月終止3G 服務後，今日 2G全面退網，標誌公司率先實現雙網迭代的重要里程碑，將豐富頻譜資源與技術，優先投放至 5G 及 5.5G 網絡建設，全面提升網絡容量、覆蓋效率及智能化管理，為客戶帶來更高速、低時延且更穩定的流動通訊體驗，並全方位投入人工智能應用、物聯網、行業數碼化及智慧城市創新的蓬勃發展，為香港長遠的網絡架構與資訊科技建設奠定堅實基礎。

AI技術賦能網絡升級
是次網絡升級，公司善用 AI 技術優化整個流程：透過大數據及機器學習模型精準識別 2G用戶，並以智能外呼、短訊及 App 提醒等方式精準觸達，累計觸達客戶逾 800 萬人次；利用自主開發的 AI 智能網絡協助團隊迅速識別終端兼容性，大幅提升客服與保障效率；配合即時監測網絡質素及用戶體驗，令全網指標保持平穩，實現「迭代無感、體驗無憂」。

貼心關懷履行社會責任
中國移動香港堅持技術升級與社會責任並重，構建完善的保障體系：針對舊終端的長者客戶，主動提供一對一上門與遙距協助、大字版指南、專屬熱線及門店優先通道，確保無憂過渡；同時設立專項補貼，資助用戶更換舊終端設備，並免費更換新一代USIM 卡。此外，公司更透過掛號信寄送書面通知，並將終端補貼延長至 2026年12月31日，實現通訊體驗無縫升級。

2G網絡完成歷史任務，代表一個通訊發展的時代里程碑，亦象徵香港流動網絡正邁向更高效、更智能的新階段。未來，中國移動香港將全力聚焦 5.5G 核心發展，持續投入創新科技研發、AI 網絡智能化及智慧城市基礎設施建設，全面賦能千行百業數碼化轉型，助力香港建設成為具全球影響力的國際創新科技中心。

關於中國移動香港有限公司 
中國移動香港有限公司（簡稱「中國移動香港」）隸屬中國移動有限公司（簡稱「中國移動」），《財富》雜誌「全球500強」企業，香港聯交所股份代號：941；於1997年1月正式提供服務，成為全港首個PCS流動網絡商。

作為全球最多客戶流動網絡品牌*，公司為客戶提供創新及多元化的5G通訊服務，包括話音、數據、IDD及國際漫遊等，並一直致力發展5G與人工智慧、物聯網、雲端計算、大數據等新技術結合，幫助各行各業實現5G的應用，推動大灣區智慧城市群建設與發展。

*中國移動香港有限公司為中國移動有限公司全資附屬公司。截至2025年12月31日，中國移動有限公司在全球擁有最多流動網絡客戶。

US tech stocks slid overnight (22nd). Alphabet Inc. (GOOGL.US) closed down about 5% after Google DeepMind data scientist and Nobel laureate John Jumper announced his departure to join Anthropic. Space Exploration Technologies Corp. (SPCX.US) lowered for a third straight day, plunging 16.4% for the full session after announcing the issuance of senior unsecured bonds and disclosing that it holds approximately USD100.8 billion in cash.

Futures for the three major US stock indices moved sharply lower. DJIA futures plunged 389 points or 0.7% to 51,730. S&P 500 futures and Nasdaq futures dropped 1.5% and 2.6%, respectively. US memory chip and optical module stocks collapsed in pre-market trading. Intel Corporation (INTC.US), Sandisk Corporation (SNDK.US), Marvell Technology, Inc. (MRVL.US) and Micron Technology, Inc. (MU.US) tumbled more than 7%. Seagate (STX.US) cascaded nearly 7%.

Corning Incorporated (GLW.US), Arm Holdings plc (ARM.US), Advanced Micro Devices, Inc. (AMD.US), Lumentum Holdings Inc. (LITE.US) and QUALCOMM Incorporated (QCOM.US) shrank more than 5%. AI chipmaker NVIDIA Corporation (NVDA.US) dived nearly 3% in pre-market trading. Space Exploration Technologies Corp. (SPCX.US) extended losses by 2.6% pre-market.

Expectations of further US rate hikes intensified. New York gold futures for August delivery sank 2.2% to USD4,112 per ounce. Silver futures for July delivery lost 5.4% to USD62 per ounce. Risk assets were under pressure, with Bitcoin last at USD62,560, down 2.4%, and Ethereum down 4.7% to USD1,663. New York oil futures and Brent oil futures dipped 0.6% and 0.9% to USD73.4 and USD77.3 per barrel, respectively.
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MUNICH, June 23, 2026 /PRNewswire/ -- On June 22, 2026, CATL officially unveiled the TENER Sodium Energy Storage System, the world's first real-world validated sodium-ion energy storage solution in Munich, Germany. The solution has reached full commercial maturity across technology, production capacity, and supply chain readiness. Cumulative shipments are expected to reach 1 GWh by the end of 2026, with global deliveries to begin in June 2027.

"CATL is committed to promoting energy independence around the world while delivering long term value for our customers. To achieve this we have made it our mission to develop a new battery chemistry based upon abundant resources available across all continents, one that can support the energy needs of all eight billion people, while offering longer cycle life and enhanced safety" said William Wu, Director of CATL's Energy Storage Technology Center, at the launch event. " We believe that sodium and lithium together will form the twin foundations of the future energy storage system."

TENER Sodium: Certainty for an Uncertain Future

As the share of renewable energy continues to rise and AI-driven power demand surges, energy storage is moving from a supporting role to critical infrastructure for the global energy system. However, conventional energy storage has relied heavily on lithium-based systems, whose concentrated supply and volatile prices pose growing supply chain risks. Sodium—over 1,000 times more abundant than lithium and widely distributed—offers better extreme-temperature performance, safety, and cost potential, making a technology transition in energy storage inevitable.

"The energy storage industry has moved beyond a race for scale. Today, success is increasingly defined by the ability to create long-term value," said Amanda Xu, CTO ESS and President of ESS Europe CATL, in her keynote speech. "The principle we most firmly believe in is that readiness creates certainty."

And this is precisely the mission of TENER Sodium.

Powered by CATL's latest sodium-ion technology, TENER Sodium delivers more than 30 MWh of rated capacity on a fully modular architecture. This architecture delivers three direct benefits for customers:

Simpler project deployment, with each single module weighing about 42 tonnes and only 34 units required for a 1 GWh site.

Greater configuration flexibility, with energy and power blocks decoupled to support flexible storage durations of 1, 2, 4, 6, and 8 hours, tailored to specific project requirements.

Lower maintenance cost, as faulty modules can be quickly isolated and replaced independently, simultaneously improving station-level system availability while reducing customer OPEX and maximizing asset utilization.

Beyond modular convenience, CATL has purpose-built a station-level platform specifically for sodium-ion systems.

1.Voltage regulation: To address the wide voltage range of sodium-ion batteries, CATL has developed a dedicated bidirectional (Bi-DC) voltage regulation system for its sodium solution. The system enables automatic voltage boosting in the low-voltage range, allowing the PCS to consistently deliver optimal output across the full range. This improves overall system round trip efficiency (RTE) by nearly 2%. For a 1 GWh energy storage station, this means millions of additional kilowatt-hours of power generation each year. The system is compatible with all major PCS products worldwide and provides stronger grid support capability.

2. BMS system: CATL has designed a BMS system for sodium-ion energy storage systems to leverage sodium chemistry's continuously sloping voltage curve, enabling more accurate SOC estimation. Furthermore, the overcharge SOC tolerance of sodium-ion batteries has been increased by 20% compared with lithium-ion batteries. This gives the BMS an additional 20% safety margin for operation, allowing greater flexibility.

3. Ultra-low auxiliary energy consumption: The unique top-discharge airflow design eliminates thermal-island effects at the source, reducing system heat generation by nearly 30% compared to conventional solutions. Combined with a highly efficient liquid-cooling system, auxiliary power consumption has been reduced from the industry average of 2% to 1%. For large-scale, long-duration energy storage projects, this improvement can save millions of euros in operating costs.

4. Low-noise design: TENER Sodium operates at only 65 decibels — 10 decibels lower than conventional systems. This helps address local community concerns commonly encountered across the industry, allowing for energy storage stations to be built closer to load centers, saving substantial transmission and distribution costs.

In addition, the TENER Sodium system is compatible with LFP systems and shares the same physical footprint. The same platform can accommodate either sodium-ion or lithium-ion batteries without changing enclosures, redesigning projects, or repeating certification processes. This flexibility to switch seamlessly between sodium-ion and lithium-ion technologies provides customers with a practical solution for managing lithium price volatility. Looking ahead, the TENER Sodium system also reserves an upgrade path to 2000V high-voltage architectures, enabling it to adapt to evolving technology routes.

A Decade in the Making: Supply Chain and Manufacturing Now Fully Commercial-Grade

TENER Sodium's comprehensive advantages in safety, returns, and reliability did not emerge overnight. CATL has been engaged in sodium-ion battery R&D since 2016, investing nearly €1.2 billion over the past decade. With more than 300 R&D professionals involved, it has accumulated more than 1,600 patent families and over 200 globally granted patents, overcome more than 100 technical challenges, and fully established the end-to-end manufacturing process from materials to cells.

Sodium-ion technology has evolved from a laboratory project to an energy storage material system with scalable capability. At present, CATL has built up manufacturing capability to deliver tens of thousands of tonnes of anode and cathode materials. Production costs for the NFPP are expected to decline further as the technology matures.

CATL is working with system integrators to build a complete closed loop ecosystem for sodium-ion energy storage, covering cell R&D, system delivery, product testing, and commercial deployment. In terms of production capacity, CATL has invested RMB 5 billion to expand sodium-ion production lines at its Fuding base, adding 40 GWh of annual capacity. The Jining base in Shandong has planned 160 GWh of sodium-ion production capacity. CATL's mass-production lines are fully commissioned and operational, ready to support large-scale deployment.

The comprehensive maturity of technology, products, supply chain, and manufacturing capability has significantly accelerated the commercialization of sodium-ion energy storage. In China, CATL will officially begin delivering its first sodium-ion energy storage systems to customers this September, with cumulative shipments expected to reach 1 GWh by the end of 2026. International deliveries are scheduled to begin in June 2027.

In April 2026, CATL and HyperStrong signed the world's largest sodium-ion commercial contract — a three-year, 60 GWh energy storage order — marking the official entry of sodium-ion energy storage into the GWh-scale deployment era.

Next-Generation Energy Storage: Building Certainty for the Future Grid

From pioneering LFP as the mainstream chemistry for energy storage, to defining the first-generation dedicated energy storage cells of 280Ah and 314Ah and the second-generation 587Ah cell, and now to launching its first real-world validated sodium-ion energy storage system, every standard transition by CATL has moved the industry one step forward.

The launch of the CATL TENER Sodium Energy Storage System marks a new stage in which lithium and sodium together form the twin foundation of next-generation energy storage infrastructure, supporting the energy transition for decades to come. As TENER Sodium makes its global debut and moves steadily toward mass delivery, CATL and its global partners are working together to turn the strategic vision into tangible reality — a more stable, cost-effective, and sustainable foundation for the world's energy future.

The United States and Iran reportedly reached an agreement to end military operations in Lebanon, after which the US announced a 60-day temporary waiver on sanctions against Iranian oil. Major Asia-Pacific markets broadly declined this morning (23rd). South Korean stocks plunged more than 8%, Hong Kong stocks hit another one-year low, while Singapore outperformed the region by notching a record high.

Mainland China’s three major A-share indices moved lower. The Shanghai Composite Index dipped 0.6% in the afternoon session, the Shenzhen Component Index dropped 2.3%, and the ChiNext Index slid 2.9%. Hong Kong stocks extended a four-day losing streak. The HSI was last at 23,447 pts, down 321 pts or 1.3%, with turnover at HKD210.136 billion. Taiwan stocks ebbed from record highs, down 455 pts or 0.95% to 47,285. TSMC lost 0.2% and Hon Hai dived 3.2%.

Japan's Nikkei pulled back from record highs, collapsing 1,808 pts or 2.5% in the afternoon session to 70,545. Memory chip maker Kioxia once tumbled 16%, marking its biggest drop since November 2025. SoftBank slumped 8.9%. Ajinomoto, which produces semiconductor insulating materials, tumbled 6.4%. MLCC manufacturer Murata Manufacturing sank 5.6%. Citi said ample global liquidity has created favorable conditions for capital inflows into Japanese equities. The rally since April remains within a healthy range without reflecting excessive speculation or bubble conditions, and Citi raised its Nikkei target to 90,000.

South Korea’s KOSPI plummeted 739 pts or 8.1% to 8,375, triggering a circuit breaker and halting trading for 20 minutes. Regulators are studying stabilization measures for leveraged products tied to individual domestic stocks. Two heavyweight stocks dragged the market lower, with Samsung Electronics nosediving 7.8% and SK Hynix cascading 10.5%. MLCC maker Samsung Electro-Mechanics slipped 9.2%, and Hyundai Motor slid 10.6%. The market is closely watching results from global memory chip giant Micron Technology, Inc. (MU.US) due later this week.
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Demand for electric vehicles (EVs) in Europe continued to bolster growth in the local auto market in May, offsetting a plunge in gasoline and diesel sales and helping Chinese brands garner greater market share, data released by the European Automobile Manufacturers' Association (ACEA) showed.

Europe's car registrations climbed 3.6% in May to 1.1525 million units, while registrations in the first five months of the year mounted 4.5% YoY. On the back of newly revised tax incentives and subsidy programs, European consumers showed strong demand for EVs.

In contrast, Chinese automakers delivered standout performances. LEAPMOTOR (09863.HK) saw May sales surge of 465.1%, while CHERY AUTO (09973.HK) and BYD COMPANY (01211.HK) posted leaps of 244.1% and 136.6%, respectively. GEELY AUTO (00175.HK) and SAIC Motor also logged increases of 12.6% and 13.9%, respectively.

As for Tesla (TSLA.US), it achieved a rebound for the fourth consecutive month, with registrations soaring 107.9% to 286,100 units.
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Meta Platforms, Inc. (META.US) poured USD900 million in Indian fintech startup Cred, acquiring an approximately 20% stake, with plans to appoint Cred founder Kunal Shah as the new head of WhatsApp.

Cred operates an App that rewards users for paying their credit card bills on time. Cred is currently valued at USD4.5 billion post-investment.

Shah will succeed current WhatsApp head Will Cathcart, who has led WhatsApp for about seven years. During his tenure, WhatsApp's user base more than doubled.

A Meta spokesperson declined to disclose details of Cathcart’s next project.
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Attracting over 15.7 million MICE visits since 2007
Elevating Macao's international competitiveness through long-term
non-gaming investment

MACAO, June 22, 2026 /PRNewswire/ -- Since the opening of Sands^® Macao in 2004, Sands China Ltd. has remained committed to contributing to Macao's development into a World Centre of Tourism and Leisure. As a trailblazer of Macao's integrated resort model, Sands China has placed hospitality, retail, entertainment, and MICE (meetings, incentives, conferences and exhibitions) at the core of its non-gaming development strategy. For over two decades, the company has continuously invested in both infrastructure and software to broaden the scope and depth of the city's industries, in support of the Macao SAR government's economic diversification direction.

With the opening of The Venetian^® Macao in 2007, Sands China took a forward-looking approach by establishing Cotai Expo, the largest MICE facility in Macao — laying a solid foundation for the city's international competitiveness in the MICE industry. Over the years, the company has been steadfast in advancing non-gaming development, driving Macao's MICE sector to evolve from an emerging industry into a high-growth pillar. Sands China successfully developed and enriched the integrated model that enables multiple experiences within a single stop. To date, the company's total MICE facilities span over 1.6 million square feet, continuing to scale the international and professional development of the sector.

Under strong policy support from both the central and Macao SAR governments, Macao's MICE industry has expanded significantly, becoming one of the key engines driving progress in the city's diversification. Sands China has long played a proactive role in promoting the industry's advancement. It has leveraged its world-class integrated resorts to enhance Macao's capacity and competitiveness in hosting large-scale international MICE events, successfully attracting a wide range of globally influential, high-value conferences and exhibitions to the city.

As of now, Sands China has hosted nearly 12,800 MICE events across a broad spectrum of global industries, attracting over 15.7 million MICE visits from around the world. These efforts continue to strengthen Macao's position as one of the premier MICE tourism destinations in Greater China, Asia, and globally.

Sands China firmly believes that MICE serves as a powerful economic multiplier, conducive to fostering the development of related industries. Its strong international connectivity also enables the city to attract a broad base of global business travellers and professionals, further expanding Macao's international source markets. Sands China has long tapped into the continued hosting of high-quality international MICE events as part the company's approach to elevate Macao's appeal to global tourists. In 2025 alone, Sands China recorded 380,000 room nights by international guests across its integrated resorts.

Grant Chum, chief executive officer and executive director of Sands China Ltd., said: "Over the years, Sands China has played a pivotal role in developing Macao's MICE industry, integrating MICE deeply within our integrated resort model. We have built large-scale, high-quality MICE infrastructure in Macao, continuously elevating the sector into a strategic drawcard and tourism product that connects Macao with global markets, strengthens the city's international competitiveness, and supports its broader economic diversification. Since 2007, Sands China has attracted over 15.7 million MICE visits. As the local MICE industry continues to flourish, Macao has increasingly established itself as one of the world's most influential business and tourism destinations, underscoring the sector's contribution to the city's diversified economic growth.

"Looking ahead, Sands China will continue to align closely with the Macao SAR government's 'Tourism+' policy. Through the continued strengthening of synergies across non-gaming sectors, our company endeavours to further elevate Macao's global competitiveness and appeal, while supporting the development of its diversified economy, and remains committed to consolidating the city's position as a World Centre of Tourism and Leisure."

Sands China holds unwavering confidence in Macao's long term development trajectory. As the company continues to strengthen its business performance, it maintains its commitment to long-term investment in the city. The company is proactively deepening high-quality, non-gaming "Tourism+" initiatives to support Macao's overall development strategy –– striving to further enrich Macao's appeal as a City of Events and contribute to its long-term, sustainable and diversified growth.

About Sands China Ltd. 
Sands China Ltd. (Sands China or the Company) is incorporated in the Cayman Islands with limited liability and is listed on The Stock Exchange of Hong Kong Limited (HKEx: 1928). Sands China is the largest operator of integrated resorts in Macao. The Company's integrated resorts on the Cotai Strip comprise The Venetian^® Macao, The Plaza^® Macao, The Parisian^® Macao and The Londoner^® Macao. The Company also owns and operates Sands^® Macao on the Macao peninsula. The Company's portfolio features a diversified mix of leisure and business attractions and transportation operations, including large meeting and convention facilities; a wide range of restaurants; shopping malls; world-class entertainment at The Venetian Arena, The Londoner Arena, The Venetian Theatre, The Parisian Theatre, The Londoner Theatre and Sands Theatre; and a high-speed Cotai Water Jet ferry service between Hong Kong and Macao. The Company's Cotai Strip portfolio has the goal of contributing to Macao's transformation into a world centre of tourism and leisure. Sands China is a subsidiary of global resort developer Las Vegas Sands Corp. (NYSE: LVS).

For more information, please visit www.sandschina.com.

Media contacts:
Corporate Communications, Sands China Ltd.
Mabel Wu
Tel: +853 8118 2268
Email: [email protected]

Jesse Chiang
Tel: +853 8118 2054
Email: [email protected]

自二零零七年至今吸引逾1,570萬人次參展
共建城市國際競爭力   彰顯持續非博彩投入 

澳門2026年6月22日 /美通社/ -- 自2004年澳門金沙開業至今，金沙中國一直與澳門並肩同行，致力為澳門發展成為世界旅遊休閒中心貢獻力量。作為澳門綜合度假村營運模式的先驅，公司以酒店、零售、娛樂及會展等非博彩業務板塊作為企業發展核心，二十多年來全力配合澳門特區政府經濟適度多元發展的施政方針，從不間斷投放軟硬件資源，驅動澳門產業多元發展。

金沙中國於2007年澳門威尼斯人^®開幕時，已率先前瞻性打造全澳最大規模的會展設施「金光會展」，為澳門的會展發展奠基國際競爭力。歷經多年發展，公司持續聚焦非博彩多元發展布局，助力推動會展業從探索階段走向高速增長，成功構建及豐富「一程多站」的整合發展模式。時至今日，旗下會展設施總面積已擴大至逾160萬平方呎，持續推動澳門會展業的國際化、專業化及規模化發展。

在中央人民政府及澳門特區政府的政策大力推動下，澳門會展業的發展空間得以不斷拓展，並逐步發展成為城市經濟適度多元的重要引擎之一。金沙中國作為澳門會展業的積極推動者，多年來充分發揮旗下世界級綜合旅遊休閒設施的優勢，為澳門提升舉辦大型會展活動的承載能力及競爭力，成功吸引眾多具全球影響力的高端會展項目落戶澳門。截至目前，公司在澳門累計舉辦近12,800項會展活動，當中涵蓋多個全球前沿行業領域，共吸引來自全球一共逾1,570萬人次參展，持續推動澳門成為大中華、亞洲、以至全球的重要會展旅遊目的地之一。

金沙中國深信，會展業具有強大的產業聯動效益，不僅帶動眾多關聯行業提質升級，更憑藉會展業的國際聯通性，匯聚大批國際專業人士及商務旅客，為澳門拓展更廣闊的國際客源市場。多年來，金沙中國透過引進及舉辦國際高端會展活動，不斷強化澳門對國際旅客的吸引力。單在2025年，公司旗下國際客入住晚數達380,000 住宿晚。

金沙中國有限公司行政總裁兼執行董事鄭君諾先生表示：「金沙中國多年來成功延展本澳會展業發展，將會展業深度融入綜合休閒度假村的營運及發展模式之中，並為澳門構建出具規模、高質量的會展基建，持續推動會展業成為澳門連接世界、提升國際競爭力及推動城市多元發展的重要名片及旅遊產品。自二零零七年至今，公司已累計吸引逾1,570萬人次參展；隨著本澳會展業發展成熟，澳門更成為具全球影響力的商務旅遊目的地之一，充分印證會展業的穩健發展為澳門多元產業注入強勁動能。未來，公司將持續全力配合澳門特區政府『旅遊+』的施政方針，確保非博彩產業的聯動效益，全面促進澳門經濟多元發展，進一步提升澳門全球競爭力及吸引力，助力鞏固澳門『世界旅遊休閒中心』的定位。」

金沙中國對澳門未來發展充滿信心，在提升業務發展的同時，公司將持續投放資源，全力對接澳門特區政府的整體發展策略，積極拓展高質量「旅遊+」非博彩項目，豐富澳門「盛事之都」內涵與吸引力，為澳門經濟適度多元發展注入長期動能。

關於金沙中國有限公司

金沙中國有限公司（香港聯交所：1928，「金沙中國」或「公司」）是一所於開曼群島註冊成立的有限公司及在香港聯合交易所有限公司上市的公司。金沙中國是澳門最大的綜合度假村經營商，於路氹金光大道上設有澳門威尼斯人^®、澳門百利宮、澳門巴黎人^®，以及澳門倫敦人^® 等物業項目，同時擁有及經營位於澳門半島的澳門金沙。公司旗下的各綜合度假村集合多樣化的娛樂消閒、商務設施及客運業務，包括大型會議及展覽場地、各式餐廳食肆、購物中心、於威尼斯人綜藝館、倫敦人綜藝館、威尼斯人劇場、巴黎人劇場、倫敦人劇場及金沙劇場舉行的世界級娛樂表演，以及來往港澳的金光飛航高速渡輪服務。公司在路氹金光大道的各物業發展項目，堅定並持續地為建設澳門成為世界旅遊休閒中心貢獻力量。金沙中國是全球度假村發展商拉斯維加斯金沙集團股份有限公司（紐約證券交易所：LVS）的附屬公司。

如欲索取更多相關資訊，請瀏覽網頁https://hk.sandschina.com/index.html。

傳媒查詢：

金沙中國有限公司 – 企業傳訊部
胡美寶
電話：+853 8118 2268
電郵：[email protected] 

鄭文軒
電話：+853 8118 2054
電郵：[email protected]

- 該研究證實，EGFR-TKI可誘導DTP細胞TROP2上調，為sac-TMT與EGFR-TKI聯合用藥提供機制依據。

- 公司正在開展兩項臨床試驗：sac-TMT聯合奧希替尼一線治療晚期EGFR突變NSCLC的III期注冊研究（已完成受試者入組，現處於隨訪階段）；以及該聯合方案用於可切除EGFR突變NSCLC新輔助治療的II期研究。

- sac-TMT已在中國獲批用於既往經TKI單藥治療後進展、或經TKI聯合含鉑化療後進展的晚期EGFR突變NSCLC，且在TKI耐藥人群中展現出顯著PFS與OS獲益。

成都2026年6月22日 /美通社/ -- 四川科倫博泰生物醫藥股份有限公司（以下簡稱「科倫博泰」或「公司」）宣布，旗下蘆康沙妥珠單抗（sac-TMT，研發代號：SKB264/MK-2870，商品名：佳泰萊^®）聯合奧希替尼一線治療晚期表皮生長因子受體(EGFR)突變非小細胞肺癌(NSCLC)的轉化研究成果已在線發表於國際學術期刊《Cancer Cell》。

該論文題為「Targeting TROP2 in drug-tolerant persister cells delays EGFR tyrosine kinase inhibitor resistance in non-small-cell lung cancer」，由中山大學腫瘤防治中心張力教授、方文峰教授團隊牽頭完成。研究顯示，經EGFR酪氨酸激酶抑制劑(TKI)治療後，殘存的藥物耐受持久性細胞(DTP)會出現滋養層細胞表面抗原2(TROP2)表達上調；臨床前模型證實，sac-TMT聯合奧希替尼可抑制DTP細胞形成並延緩腫瘤復發。上述研究結果為靶向TROP2抗體藥物偶聯物(ADC)與EGFR-TKI聯合用於延緩耐藥提供了轉化醫學證據，進一步凸顯sac-TMT作為EGFR-TKI核心聯合用藥搭檔的差異化價值。

基於上述研究成果與臨床開發計劃，公司正在推進一項III期注冊研究（試驗編號：NCT06670196），將sac-TMT聯合奧希替尼與奧希替尼單藥一線治療局部晚期或轉移性EGFR突變非鱗狀NSCLC進行對比。該研究旨在評估sac-TMT（4 mg/kg，每兩周給藥一次）聯合奧希替尼相較於奧希替尼單藥在此適應症下的療效與安全性。該研究已在中國完成全部受試者入組，目前進入隨訪與數據成熟階段。

除此之外，公司還在推進sac-TMT用於更早期EGFR突變NSCLC的臨床探索。一項II期臨床研究（試驗編號：NCT07329322）正在開展，評估sac-TMT聯合奧希替尼或sac-TMT單藥用於可切除EGFR突變NSCLC新輔助治療，進一步挖掘sac-TMT在圍手術期治療中的潛在價值。

本次研究成果刊發於《Cancer Cell》夯實了sac-TMT聯合EGFR-TKI一線治療EGFR突變NSCLC的科學理論基礎。依托sac-TMT在EGFR突變NSCLC領域已獲批的適應症及臨床開發計劃，公司將持續探索該聯合方案在前線治療、耐藥延緩、長期生存獲益等方面的應用潛力。科倫博泰將持續深耕EGFR突變NSCLC創新治療方案的研發，為患者提供更多治療選擇。

關於sac-TMT（佳泰萊^®）

作為公司的核心產品，sac-TMT是一款公司擁有自主知識產權的新型人源化TROP2 ADC，適應症覆蓋NSCLC、乳腺癌(BC)、胃癌(GC)、婦科腫瘤、泌尿生殖系統腫瘤等多種晚期實體瘤。sac-TMT采用獨特雙功能連接子開發而成：一端與抗TROP2單抗沙妥珠單抗不可逆結合，另一端可在溶酶體內發生pH依賴性裂解，釋放貝洛替康衍生物拓撲異構酶I抑制劑載荷，從而最大限度地將毒性載荷遞送至腫瘤細胞，藥物抗體比(DAR)達7.4。sac-TMT通過重組抗TROP2人源化單克隆抗體特異性識別腫瘤細胞表面TROP2，經腫瘤細胞內吞後，在細胞內釋放毒性載荷KL610023。KL610023作為拓撲異構酶I抑制劑，可誘導腫瘤細胞DNA損傷，進而導致細胞周期阻滯與凋亡。此外，KL610023會被釋放至腫瘤微環境。由於KL610023具備細胞膜穿透性，可產生旁觀者效應，殺傷周邊腫瘤細胞。

2022年5月，公司授予默沙東（美國新澤西州羅威市默克公司的商號）在大中華區（包括中國大陸、香港、澳門及台灣）以外的全球所有地區開發、使用、制造及商業化sac-TMT的獨家權利。

截至目前，sac-TMT在中國已獲批四項適應症並實現商業化上市：1)既往接受至少兩種系統治療（其中至少一種治療針對晚期/轉移性階段）的不可切除局部晚期或轉移性三陰性乳腺癌(TNBC)；2)經EGFR-TKI聯合含鉑化療後進展的EGFR突變陽性局部晚期或轉移性非鱗狀NSCLC；3)經EGFR-TKI單藥治療後進展的EGFR突變陽性局部晚期或轉移性非鱗狀NSCLC；4)既往接受內分泌治療且晚期階段至少接受過一線化療的不可切除或轉移性激素受體陽性(HR+)、人表皮生長因子受體2陰性（HER2-，免疫組織化學(IHC) 0、IHC 1+或IHC 2+/原位雜交(ISH)-) BC。上述前兩項適應症已納入中國國家醫保藥品目錄(NRDL)，有望為更多BC和NSCLC患者帶來具有臨床意義的生存獲益。同時，sac-TMT已獲中國國家藥品監督管理局(NMPA)授予六項突破性療法認定(BTD)。

sac-TMT是全球首個在肺癌適應症領域獲批上市的TROP2 ADC藥物。sac-TMT的新增適應症上市申請已獲NMPA受理，用於聯合帕博利珠單抗（可瑞達^®[1]）一線治療腫瘤細胞程序性死亡配體1(PD-L1)腫瘤細胞陽性比例評分(TPS)≥1%、EGFR陰性/間變性淋巴瘤激酶(ALK)陰性的局部晚期或轉移性NSCLC，並進入優先審評審批通道。截至當前，科倫博泰已在中國啟動9項注冊臨床研究。默沙東正在全球開展17項III期臨床研究，評估sac-TMT單藥或聯合帕博利珠單抗或其他抗癌藥物用於多種類型癌症的治療。這些研究均由默沙東發起並牽頭。

關於科倫博泰

科倫博泰（股票代碼：6990.HK）是科倫藥業旗下控股子公司，專注創新生物藥和小分子藥物的研發、生產、商業化及全球合作。公司聚焦實體瘤、自身免疫疾病、代謝性疾病等重大疾病領域，搭建全球化藥物研發與產業化平台，滿足國內外未被滿足的臨床用藥需求，致力於成為全球領先的創新藥企。目前，公司擁有30余個在研核心創新藥項目，其中4個項目共8個適應症已獲批上市，1個項目處於新藥上市申請(NDA)階段，十余個項目進入臨床研究階段。公司成功構建了全球領先的專有ADC與新型DC技術平台OptiDC™，現有2款ADC產品共5個適應症已獲批上市，多款ADC及新型DC產品處於臨床或臨床前研究階段。有關更多詳情，請訪問官網：https://en.kelun-biotech.com/